Product image of Montelukast Teva (Montelukast Sodium) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Teva (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as a tablet for oral use. It is used to manage chronic asthma and to relieve symptoms of seasonal and perennial allergic rhinitis in adults and children.

GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Sweden Ab

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Indications & Clinical Uses

  • Montelukast Teva, a leukotriene receptor antagonist, is indicated for conditions involving airway inflammation and allergic responses.
  • Asthma (maintenance therapy): reduces frequency of bronchoconstriction episodes and improves overall lung function.
  • Seasonal allergic rhinitis: alleviates nasal congestion, sneezing, and itchy eyes during pollen seasons.
  • Perennial allergic rhinitis: controls year‑round nasal symptoms caused by indoor allergens.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor type 1 (CysLT1) on airway smooth muscle, inflammatory cells, and vascular endothelium. By antagonizing this receptor, it prevents leukotriene D4, E4 and related mediators from binding, thereby inhibiting bronchoconstriction, mucus secretion, vascular permeability, and eosinophilic inflammation that contribute to asthma and allergic rhinitis.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea
  • Dizziness
  • Fatigue

Serious or Rare Side Effects

  • Angioedema or swelling of the face, lips, or throat
  • Eosinophilic granulomatosis with polyangiitis (Churg‑Strauss syndrome)
  • Severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Hepatic injury or abnormal liver function tests
  • Mood changes including depression or suicidal thoughts
  • Anaphylactic reactions

Precautions & Warnings

  • When prescribing Montelukast, clinicians should consider several safety precautions to minimize risk.
  • Assess asthma control: ensure patient is on appropriate inhaled therapy before adding Montelukast.
  • Monitor for allergic reactions: watch for signs of rash, swelling, or respiratory distress.
  • Review concomitant medications: avoid drugs that strongly induce or inhibit CYP enzymes.
  • Evaluate hepatic function: consider baseline liver tests in patients with liver disease.
  • Use caution in patients with psychiatric history: monitor for mood changes or suicidal ideation.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Montelukast can interact with other medicines that affect its metabolism or pharmacodynamic profile.

Major Interactions (Avoid)

  • Phenobarbital, carbamazepine, or rifampin: strong CYP3A4 inducers that markedly reduce Montelukast exposure.
  • Ketoconazole, itraconazole, or other potent CYP3A4 inhibitors: may increase systemic levels and risk of adverse effects.
  • Warfarin: concurrent use may alter anticoagulant effect; close monitoring required.

Moderate Interactions (Monitor Closely)

  • Theophylline: possible additive bronchodilator effect; observe for increased side effects.
  • Beta‑agonists (e.g., albuterol): combined use may enhance bronchodilation but requires symptom monitoring.
  • Antidepressants or antipsychotics: monitor for potential additive central nervous system effects.

Frequently Asked Questions

Montelukast Teva is prescribed for the long‑term management of asthma as a maintenance therapy and for relief of symptoms associated with both seasonal and perennial allergic rhinitis. It helps reduce bronchospasm in asthma and alleviates nasal congestion, sneezing, and itching caused by allergic triggers.

Montelukast Sodium works by selectively blocking the cysteinyl leukotriene receptor type 1 (CysLT1). This inhibition prevents leukotrienes—potent inflammatory mediators—from binding to airway smooth muscle and other tissues, thereby reducing bronchoconstriction, mucus production, vascular leakage, and eosinophilic inflammation that underlie asthma and allergic rhinitis.

The appropriate dose of Montelukast Teva is set by the prescribing clinician based on the patient’s age, weight, severity of asthma or allergic rhinitis, and any concomitant therapies. The product is available only by prescription, and the prescriber will decide the exact strength and frequency that best matches the individual’s therapeutic needs.

Safety data for Montelukast during pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies any possible risk to the fetus. Regarding lactation, small amounts may pass into breast milk; a healthcare professional should evaluate the risk‑benefit balance before continuing therapy while nursing.

To place an order, submit an enquiry on the Montelukast Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.

Montelukast is a leukotriene receptor antagonist, whereas inhaled corticosteroids (ICS) target a broader range of inflammatory pathways. Montelukast is often added as an adjunct to ICS for patients whose symptoms are not fully controlled, or used when inhaler technique is problematic. It offers oral administration, which can improve adherence, but it does not replace the anti‑inflammatory potency of high‑dose corticosteroids.

Montelukast Teva tablets should be stored at room temperature, below 25 °C. Keep them in the original blister or container, protect from moisture, direct sunlight, and excessive heat. Do not store in the bathroom or near a kitchen sink where humidity is high, and keep the product out of reach of children.

Montelukast Teva is taken orally, usually once daily in the evening with or without food, as directed by the prescriber. The tablet should be swallowed whole with a glass of water. Patients should follow the specific dosing schedule provided by their healthcare professional and should not split, crush, or chew the tablet unless instructed otherwise.

Serious adverse events, although rare, include angioedema, eosinophilic granulomatosis with polyangiitis (formerly Churg‑Strauss syndrome), severe skin reactions such as Stevens‑Johnson syndrome, hepatic injury, and neuropsychiatric effects like depression or suicidal thoughts. Any signs of swelling, rash, mood changes, or liver dysfunction should prompt immediate medical evaluation.

Montelukast Teva is contraindicated in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. Patients with a history of severe allergic reactions, uncontrolled psychiatric illness, or those who have experienced serious leukotriene‑mediated disorders should avoid the medication unless a specialist determines it is safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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