Product image of Montelukast Teva Uk (Montelukast) supplied by GNH India

Montelukast Teva Uk

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Teva Uk (Montelukast)

Montelukast, the active ingredient in Montelukast Teva Uk, is a leukotriene receptor antagonist presented as a tablet for oral use. It blocks cysteinyl leukotriene receptors, helping to control airway inflammation and nasal symptoms. The medication is indicated for the treatment of asthma and allergic rhinitis in both adult and pediatric patients.

GNH India supplies Montelukast Teva Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets.

Manufacturer / TM Owner

Teva Uk Limited

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Indications & Clinical Uses

  • Montelukast acts on the leukotriene pathway to reduce inflammation in respiratory conditions.
  • Asthma: improves long‑term control and reduces the frequency of exacerbations.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itchy eyes.
  • Exercise‑induced bronchoconstriction: prevents bronchospasm triggered by physical activity.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes D4, E4 and related mediators from binding. By inhibiting this receptor, the drug reduces bronchial smooth‑muscle contraction, vascular permeability, mucus secretion and eosinophilic inflammation, thereby improving airway patency and nasal mucosa function. The effect is sustained with once‑daily dosing, providing consistent blockade of leukotriene‑mediated pathways throughout the day.

Side Effects

Montelukast may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache
  • Abdominal pain
  • Nausea
  • Dizziness

Serious or Rare Side Effects

  • Allergic reactions (rash, angioedema, anaphylaxis)
  • Neuropsychiatric events (mood changes, depression, suicidal thoughts)
  • Hepatic injury (elevated liver enzymes, hepatitis)

Precautions & Warnings

  • When prescribing Montelukast, clinicians should consider several safety measures.
  • Assess asthma control before initiating therapy: ensure patient is on appropriate baseline treatment.
  • Monitor for neuropsychiatric symptoms: watch for mood changes or suicidal thoughts.
  • Use with caution in patients with hepatic impairment: dose adjustment may be required.
  • Avoid in individuals with known hypersensitivity to montelukast or any formulation components.
  • Review concomitant medications for potential interactions, especially CYP3A4 modulators.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast can interact with other medicines, requiring attention to the level of risk.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase montelukast plasma levels.
  • Concurrent use with other leukotriene pathway inhibitors (e.g., zafirlukast, zileuton): risk of additive adverse effects.
  • Phenobarbital or other enzyme inducers: may reduce therapeutic effect of montelukast.

Moderate Interactions (Monitor Closely)

  • Warfarin: montelukast may affect INR, requiring closer monitoring.
  • Beta‑agonists (e.g., albuterol): additive bronchodilation may occur, adjust dosing if needed.
  • Antidepressants or antipsychotics: potential for enhanced neuropsychiatric side effects.

Frequently Asked Questions

Montelukast Teva Uk is prescribed to manage chronic asthma and to alleviate symptoms of allergic rhinitis such as nasal congestion, sneezing, and itchy eyes. It may also be used to prevent exercise‑induced bronchoconstriction in patients who experience airway narrowing during physical activity.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor CysLT1. This inhibition prevents leukotrienes—potent inflammatory mediators—from binding to airway smooth muscle and nasal tissues, thereby reducing bronchoconstriction, mucus production, and inflammatory cell infiltration.

The exact dose of Montelukast Teva Uk is set by the prescribing healthcare professional based on the patient’s age, weight, severity of disease, and response to therapy. No universal dosing regimen is provided here; the prescriber tailors the regimen to each individual’s clinical needs.

Safety data for montelukast in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant. Patients who are pregnant, planning pregnancy, or breastfeeding should discuss the decision with their physician.

To request Montelukast Teva Uk, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids and long‑acting beta‑agonists. While it is effective for mild‑to‑moderate asthma and allergic rhinitis, it is generally used as an add‑on therapy rather than a sole replacement for inhaled steroids in severe disease.

Montelukast Teva Uk should be stored at room temperature, preferably below 25 °C. Keep the tablets in their original blister pack, protect them from moisture, direct sunlight, and excessive heat to maintain potency throughout the shelf life.

Montelukast is taken orally as a tablet. The tablet should be swallowed whole with water, typically once daily in the evening, unless the prescriber advises a different schedule. No crushing, chewing, or splitting is recommended unless specifically instructed.

The most serious risks include neuropsychiatric events such as mood changes, depression, or suicidal thoughts, severe allergic reactions like anaphylaxis, and hepatic injury manifested by elevated liver enzymes or hepatitis. Patients should seek immediate medical attention if any of these symptoms develop.

Montelukast should not be used by individuals with a known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with severe liver disease, and it is generally avoided in those who have experienced serious neuropsychiatric reactions to leukotriene modifiers.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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