Product image of Montelukast Unimark (Montelukast Sodium) supplied by GNH India

Montelukast Unimark

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Unimark (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Unimark, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is employed in the maintenance treatment of asthma and to relieve symptoms of allergic rhinitis in adults and children.

GNH India supplies Montelukast Unimark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Its global distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Unimark Remedies Sro

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Indications & Clinical Uses

Montelukast Unimark, a leukotriene receptor antagonist, is used to manage conditions driven by leukotriene‑mediated inflammation.

  • Asthma: improves long‑term control and reduces frequency of exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itchy eyes.
  • Exercise‑induced bronchoconstriction: lessens airway narrowing that occurs after physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes D4, E4 and related mediators from binding. This inhibition reduces bronchoconstriction, vascular permeability, mucus secretion and inflammatory cell recruitment that contribute to asthma and allergic rhinitis symptoms.

Side Effects

Adverse reactions may occur with any medication. The following are reported for Montelukast Unimark.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea

Serious or Rare Side Effects

  • Allergic reactions such as rash or angioedema
  • Mood changes including depression or suicidal thoughts
  • Elevated liver enzymes or hepatic dysfunction
  • Severe skin reactions such as Stevens‑Johnson syndrome

Precautions & Warnings

Before prescribing Montelukast Unimark, clinicians should consider several safety aspects.

  • Pregnancy: consult a healthcare professional as safety data are limited.
  • Breastfeeding: weigh potential benefits against unknown risks.
  • Pediatric use: follow prescriber guidance for age‑appropriate dosing.
  • Drug interactions: review all concomitant medicines for possible effects.
  • Renal or hepatic impairment: dose adjustment may be required.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture.

Avoid Interactions

Montelukast may interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin) can markedly lower montelukast exposure.
  • Phenobarbital may reduce plasma concentrations and diminish efficacy.

Moderate Interactions (Monitor Closely)

  • Certain antidepressants (e.g., fluoxetine) may increase risk of neuropsychiatric events.
  • Phenylbutazone can raise montelukast levels.
  • Warfarin may experience altered anticoagulant effect, requiring INR monitoring.

Frequently Asked Questions

Montelukast Unimark is indicated for the long‑term maintenance treatment of asthma, for relief of symptoms associated with seasonal or perennial allergic rhinitis, and for the prevention of exercise‑induced bronchoconstriction in patients who meet the prescribing criteria.

Montelukast acts as a selective antagonist of the cysteinyl leukotriene receptor CysLT1. By blocking this receptor, it prevents leukotrienes from causing bronchoconstriction, airway edema, mucus production and inflammatory cell recruitment, thereby improving breathing and reducing allergic symptoms.

The dose of Montelukast Unimark is determined by the prescribing clinician based on the patient’s age, indication and clinical response. The prescriber will select the appropriate strength and dosing schedule that best fits the individual’s therapeutic needs.

Safety data for Montelukast in pregnancy are limited, and it is classified as a category where benefits must outweigh potential risks. During breastfeeding, only limited information is available; clinicians should assess the risk‑benefit ratio before continuing therapy.

To place an order, submit an enquiry on the Montelukast Unimark product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients who prefer oral therapy or have aspirin‑exacerbated respiratory disease, but it may be less potent than high‑dose inhaled steroids for severe asthma control.

Montelukast Unimark should be stored at ambient temperature below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Montelukast Unimark is taken orally, usually as a tablet swallowed whole with water. It can be taken with or without food, and the dosing time (morning or evening) should follow the prescriber’s instructions to maintain consistent plasma levels.

Serious adverse events include severe allergic reactions such as rash or angioedema, neuropsychiatric effects like depression or suicidal thoughts, and rare hepatic or skin disorders such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if any of these symptoms develop.

Montelukast Unimark is contraindicated in individuals with known hypersensitivity to montelukast sodium or any of the tablet’s excipients. Caution is also advised for patients with a history of severe psychiatric disorders, liver disease, or those taking interacting medications without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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