Product image of Montelukast Viatris (Montelukast) supplied by GNH India

Montelukast Viatris

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Viatris (Montelukast)

Montelukast, the active ingredient in Montelukast Viatris, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children as indicated.

GNH India supplies Montelukast Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

  • Montelukast acts on the leukotriene pathway to control airway inflammation and bronchoconstriction.
  • Asthma: provides maintenance therapy that reduces the frequency of symptoms and exacerbations.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching associated with seasonal allergies.
  • Exercise‑induced bronchoconstriction: prevents bronchospasm triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 and related mediators from binding. This inhibition reduces bronchial smooth‑muscle contraction, vascular permeability, and inflammatory cell recruitment, thereby decreasing airway narrowing and inflammation associated with asthma and allergic airway disease.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea
  • Dizziness
  • Fatigue

Serious or Rare Side Effects

  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Neuropsychiatric events including depression, anxiety, or suicidal thoughts
  • Elevated liver enzymes
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Eosinophilic granulomatosis with polyangiitis (Churg‑Strauss syndrome)
  • Hematologic abnormalities

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.
  • Assess asthma control: ensure patient is on appropriate baseline therapy.
  • Monitor neuropsychiatric symptoms: watch for mood changes or suicidal ideation.
  • Use caution in hepatic impairment: dose adjustment may be required.
  • Review concomitant CYP‑modulating drugs: potential for altered exposure.
  • Avoid in patients with known hypersensitivity to montelukast or excipients.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Montelukast may interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole) may increase montelukast plasma levels.
  • Phenobarbital can lower montelukast concentrations, reducing therapeutic effect.
  • Rifampin may markedly decrease montelukast exposure.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors may heighten neuropsychiatric risk.
  • Beta‑agonists may produce additive bronchodilation.
  • Warfarin may experience variable anticoagulant effect; monitor INR.

Frequently Asked Questions

Montelukast Viatris is prescribed as a maintenance therapy for asthma, to relieve symptoms of allergic rhinitis such as nasal congestion and sneezing, and to prevent exercise‑induced bronchoconstriction. It works by targeting leukotriene‑mediated inflammation and bronchospasm, helping patients achieve better control of their respiratory conditions.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 and related mediators from binding. This inhibition reduces airway smooth‑muscle contraction, vascular leakage, and inflammatory cell recruitment, thereby decreasing bronchoconstriction and inflammation that underlie asthma and allergic airway disease.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, and specific clinical condition. Physicians select the regimen that best matches the individual’s therapeutic needs and adjust it as necessary during follow‑up.

Safety data for Montelukast in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assistance with import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. While inhaled steroids directly reduce airway inflammation, montelukast targets leukotriene‑mediated pathways and is useful for patients who prefer oral therapy or have specific indications such as exercise‑induced bronchoconstriction. Choice of therapy depends on disease severity, patient preference and physician assessment.

Montelukast Viatris should be stored at room temperature, below 25 °C. Keep the tablets in the original packaging to protect them from moisture and light. Do not store in humid or excessively hot environments, and keep out of reach of children.

The medication is taken orally, usually as a tablet swallowed whole with water. It is typically taken once daily, with or without food, as directed by the prescribing clinician. Consistent timing each day helps maintain steady drug levels.

Serious adverse events include allergic reactions such as rash, angioedema or anaphylaxis, and neuropsychiatric effects like depression, anxiety, or suicidal thoughts. Rare but severe complications may involve liver enzyme elevation, eosinophilic granulomatosis with polyangiitis, and severe skin reactions (e.g., Stevens‑Johnson syndrome). Patients should seek immediate medical attention if any of these occur.

Montelukast is contraindicated in individuals with known hypersensitivity to montelukast sodium or any of the tablet’s excipients. Caution is advised for patients with severe hepatic impairment, and clinicians should evaluate the risk‑benefit ratio before prescribing to such individuals.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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