Product image of Montelukast Viatris (Montelukast) supplied by GNH India

Montelukast Viatris

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Viatris (Montelukast)

Montelukast, the active ingredient in Montelukast Viatris, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children as prescribed.

GNH India supplies Montelukast Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

  • Montelukast acts on leukotriene pathways to manage several respiratory conditions.
  • Asthma: improves control and reduces frequency of bronchospasm in persistent asthma.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching associated with seasonal allergies.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 in the airways, preventing leukotriene‑mediated smooth‑muscle contraction, mucus secretion, and inflammatory cell recruitment. By inhibiting this pathway, it reduces bronchoconstriction and airway inflammation associated with asthma and allergic disorders.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Abdominal pain: occasional discomfort in the stomach area.
  • Nausea: occasional feeling of queasiness.
  • Diarrhea: loose stools occurring intermittently.
  • Cough: transient irritation of the throat.
  • Sore throat: mild irritation of the pharynx.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema, or anaphylaxis requiring immediate medical attention.
  • Neuropsychiatric events: mood changes, depression, or suicidal thoughts.
  • Liver injury: signs of hepatitis such as jaundice or elevated enzymes.
  • Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.

Precautions & Warnings

  • Before prescribing Montelukast, consider the following precautions.
  • Pregnancy: safety not established; discuss risks with a healthcare provider.
  • Breastfeeding: unknown excretion; weigh benefits against potential risks.
  • Renal impairment: use with caution and monitor renal function.
  • Hepatic impairment: dose adjustment may be needed; monitor liver enzymes.
  • Concomitant phenobarbital or rifampin: may reduce drug effectiveness.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Montelukast can interact with other medicines; monitor the following.

Major Interactions (Avoid)

  • Phenobarbital, rifampin, carbamazepine: enzyme inducers that may lower montelukast plasma levels.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase exposure, requiring caution.

Moderate Interactions (Monitor Closely)

  • Fluconazole: moderate CYP3A4 inhibition may raise montelukast levels.
  • Warfarin: occasional reports of altered INR; monitor coagulation parameters.
  • Theophylline: combined use may affect bronchodilator response.

Frequently Asked Questions

Montelukast Viatris is prescribed for the management of asthma, allergic rhinitis, and exercise‑induced bronchoconstriction. It helps control airway inflammation and reduces the frequency of bronchospasm in these respiratory disorders.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes from causing airway smooth‑muscle contraction, mucus production, and inflammatory cell recruitment. This inhibition reduces bronchoconstriction and airway inflammation, improving breathing and nasal symptoms.

The appropriate dose of Montelukast Viatris is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of disease, and clinical response. No fixed regimen is provided here; the prescriber sets the exact dosage.

Safety data for Montelukast in pregnancy are limited, and the product is classified as pregnancy category unknown. It should be used only if the potential benefit justifies the potential risk. During breastfeeding, it is unclear whether the drug is excreted in milk; clinicians should weigh benefits against possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑sensitive asthma or those who need additional control of allergic symptoms, but it does not replace rescue bronchodilators for acute attacks.

Montelukast Viatris should be stored at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and store them out of reach of children.

Montelukast Viatris is taken orally, usually as a tablet swallowed whole with water. The exact timing (e.g., morning or evening) and whether it should be taken with food are determined by the prescribing clinician.

Serious risks include severe allergic reactions such as angioedema or anaphylaxis, neuropsychiatric events like mood changes, depression or suicidal thoughts, and rare hepatic injury. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelukast Viatris is contraindicated in individuals with known hypersensitivity to montelukast or any of its excipients. Caution is advised for patients with severe hepatic impairment, and it should be avoided in those taking strong enzyme‑inducing drugs without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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