Product image of Montelukast Vir (Montelukast Sodium) supplied by GNH India

Montelukast Vir

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Vir (Montelukast Sodium)

Montelukast, the active ingredient in Montelukast Vir, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is indicated for the management of asthma and allergic rhinitis in adults and children.

GNH India supplies Montelukast Vir as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established quality‑assured manufacturing and distribution networks across the EU and other regulated markets, and the product meets EU pharmacopeial standards and is available for bulk procurement globally.

Manufacturer / TM Owner

Industria Química Y Farmaceútica Vir, S.A.

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Indications & Clinical Uses

Montelukast Vir is a leukotriene receptor antagonist used to manage conditions driven by leukotriene‑mediated inflammation.

  • Asthma: improves control of chronic asthma and reduces exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching caused by seasonal allergies.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing during or after physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 from binding. This inhibition reduces leukotriene‑mediated bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the airways, thereby improving respiratory function and decreasing allergic inflammation.

Side Effects

Montelukast may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate pain often occurring early in therapy.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Cough: transient irritation of the throat.
  • Nausea: feeling of queasiness without vomiting.

Serious or Rare Side Effects

  • Angioedema: rapid swelling of face, lips, tongue or throat.
  • Stevens‑Johnson syndrome: severe skin rash with blistering.
  • Mood changes: including depression, anxiety, or suicidal thoughts.

Precautions & Warnings

Before prescribing Montelukast Vir, clinicians should consider several safety aspects.

  • Liver function monitoring: assess hepatic enzymes in patients with liver disease.
  • Neuropsychiatric assessment: watch for mood alterations or suicidal ideation.
  • Severe hepatic impairment: use with caution and adjust therapy as needed.
  • Hypersensitivity: avoid in individuals with known allergy to montelukast or excipients.
  • Concomitant medication review: evaluate for potential drug interactions.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Montelukast Vir can interact with other medicines, requiring attention to the interaction strength.

Major Interactions (Avoid)

  • Phenobarbital: induces metabolism, reducing montelukast exposure.
  • Rifampin: strong enzyme inducer that lowers drug levels.
  • Ketoconazole: potent CYP3A4 inhibitor that may increase montelukast concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR, requiring coagulation monitoring.
  • Theophylline: may affect plasma levels, necessitating dose adjustment.
  • Beta‑agonists: concurrent use may diminish bronchodilator response.

Frequently Asked Questions

Montelukast Vir is prescribed to treat chronic asthma, allergic rhinitis, and exercise‑induced bronchoconstriction. By blocking leukotriene receptors, it helps reduce airway inflammation, improve breathing, and lessen allergy‑related nasal symptoms.

Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 from triggering bronchoconstriction and inflammatory processes in the respiratory tract. This action reduces airway narrowing and allergic inflammation.

The dose of Montelukast Vir is determined by the prescribing healthcare professional based on the patient’s age, condition severity, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Montelukast during pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the medication.

To place an order, submit an enquiry on the Montelukast Vir product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients who prefer oral therapy or have aspirin‑exacerbated respiratory disease, though inhaled steroids remain first‑line for many asthma patients.

Montelukast Vir should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture and direct sunlight to maintain stability throughout its shelf life.

Montelukast Vir is taken orally as a tablet. The tablet should be swallowed whole with water, and it can be taken with or without food according to the prescriber’s guidance.

Serious adverse events, though rare, include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, and neuropsychiatric effects like depression or suicidal thoughts. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash with blistering, or significant mood changes.

Montelukast Vir should be avoided in individuals with known hypersensitivity to montelukast or any of its excipients. Caution is also advised for patients with severe hepatic impairment, and it is not recommended for use in children under the age approved for the specific formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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