Product image of Mooncast (Montelukast) supplied by GNH India

Mooncast

Active Ingredient:
Montelukast
Origin:
EU

Mooncast (Montelukast)

Montelukast, the active ingredient in Mooncast, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It works by blocking cysteinyl leukotriene receptors in the airways, reducing inflammation and bronchoconstriction, and is indicated for the management of asthma, exercise‑induced bronchoconstriction, and allergic rhinitis in adults and children.

GNH India supplies Mooncast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Maddox Pharma Swiss B.V.

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Indications & Clinical Uses

Montelukast acts on leukotriene pathways to control airway inflammation and allergic symptoms.

  • Asthma: improves control of chronic airway inflammation and reduces frequency of exacerbations.
  • Exercise‑induced bronchoconstriction: prevents narrowing of airways triggered by physical activity.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching caused by allergic inflammation.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1 located on bronchial smooth muscle, vascular endothelium and inflammatory cells. By blocking the binding of leukotriene D4 and related mediators, it inhibits leukotriene‑induced bronchoconstriction, vascular permeability, mucus secretion and eosinophil recruitment, thereby reducing airway inflammation and hyper‑responsiveness.

Side Effects

Montelukast may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache: mild to moderate pain in the head.
  • Abdominal pain: discomfort or cramps in the stomach area.
  • Cough: transient irritation of the respiratory tract.
  • Nausea: feeling of queasiness or urge to vomit.
  • Diarrhea: loose, watery stools.
  • Fatigue: general sense of tiredness.

Serious or Rare Side Effects

  • Angioedema: swelling of the face, lips, tongue or throat.
  • Stevens‑Johnson syndrome: severe skin rash with blistering.
  • Hepatic injury: elevated liver enzymes or jaundice.
  • Neuropsychiatric events: mood changes, depression or suicidal thoughts.
  • Anaphylaxis: rapid, life‑threatening allergic reaction.

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several safety and handling measures.

  • Assess liver function: evaluate hepatic status before initiating therapy.
  • Monitor neuropsychiatric symptoms: watch for mood changes, depression or suicidal ideation.
  • Use caution in severe hepatic impairment: dose adjustment may be required.
  • Avoid in patients with known hypersensitivity to Montelukast or any tablet excipients.
  • Review concomitant medications: consider potential drug interactions.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Montelukast can interact with other medicines, altering its plasma concentration or therapeutic effect.

Major Interactions (Avoid)

  • Ritonavir: strong CYP3A4 inhibition can markedly increase Montelukast levels.
  • Phenobarbital: potent CYP3A4 induction may reduce Montelukast exposure.
  • Ketoconazole: significant CYP3A4 inhibition may raise drug concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible effect on INR; monitor coagulation parameters.
  • Beta‑agonists (e.g., albuterol): additive bronchodilation may enhance respiratory effects.
  • Theophylline: monitor for altered plasma levels and potential toxicity.

Frequently Asked Questions

Mooncast contains the active ingredient Montelukast and is prescribed to treat asthma, exercise‑induced bronchoconstriction, and allergic rhinitis. By targeting leukotriene pathways, it helps control airway inflammation, prevent bronchospasm during physical activity, and relieve nasal allergy symptoms.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, vascular leakage, and eosinophil recruitment, thereby reducing airway narrowing and allergic inflammation.

The appropriate dose of Mooncast is determined by the prescribing healthcare professional based on the patient’s age, weight, indication and clinical response. Dosage may differ for asthma, exercise‑induced bronchoconstriction or allergic rhinitis, and the prescriber will provide specific instructions.

Safety data for Montelukast in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To request Mooncast, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative to Montelukast is inhaled corticosteroids, which directly reduce airway inflammation. Montelukast offers an oral, once‑daily option that targets leukotriene‑mediated pathways and is especially useful for exercise‑induced symptoms and allergic rhinitis. Choice depends on disease severity, patient preference and physician assessment.

Mooncast tablets should be stored at room temperature, below 25 °C, in the original blister pack or container. Protect them from excess moisture, heat and direct sunlight to maintain stability and potency throughout the shelf life.

Mooncast is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, preferably at the same time each day. It can be taken with or without food, unless the prescriber advises otherwise.

Serious adverse events include neuropsychiatric reactions such as mood changes, depression or suicidal thoughts, as well as severe allergic responses like angioedema, Stevens‑Johnson syndrome and anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms.

Mooncast should be avoided in individuals with known hypersensitivity to Montelukast or any of its excipients. Caution is also advised for patients with severe hepatic impairment, and it is not recommended for use in children under the age approved for the specific indication without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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