Product image of Mopetia (Paliperidone) supplied by GNH India

Mopetia

Active Ingredient:
Paliperidone
Origin:
EU

Mopetia (Paliperidone)

Paliperidone, the active ingredient in Mopetia, is an atypical antipsychotic presented as an intramuscular injection for intramuscular use. It is indicated for the treatment of schizophrenia and schizoaffective disorder in adult patients, helping to manage psychotic symptoms and improve functional outcomes.

GNH India supplies Mopetia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Our supply chain ensures product integrity from manufacturing sites in the European Union to end‑users.

Manufacturer / TM Owner

Zentiva, K.S.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Paliperidone is an atypical antipsychotic used in the management of psychotic disorders.
  • Schizophrenia: reduces positive and negative symptoms and helps prevent relapse.
  • Schizoaffective disorder: stabilizes mood and psychotic symptoms, supporting functional recovery.

How It Works

  • Paliperidone exerts its antipsychotic effect primarily by antagonizing dopamine D2 receptors and serotonin 5‑HT2A receptors in the central nervous system. This dual receptor blockade modulates dopaminergic and serotonergic neurotransmission, reducing hyperactivity in mesolimbic pathways associated with psychosis while mitigating negative symptomatology. The drug also exhibits moderate affinity for α1‑adrenergic and histamine H1 receptors, contributing to its overall pharmacodynamic profile. These actions collectively contribute to symptom control and relapse prevention in patients with schizophrenia.

Side Effects

Paliperidone may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Akathisia: inner restlessness and urge to move.
  • Weight gain: increase in body weight.
  • Somnolence: drowsiness or sleepiness.
  • Increased prolactin: menstrual disturbances or galactorrhea.

Serious or Rare Side Effects

  • Neuroleptic malignant syndrome: life‑threatening reaction with fever, muscle rigidity, autonomic instability.
  • Tardive dyskinesia: involuntary, repetitive movements, potentially irreversible.
  • Seizures: risk of convulsions, especially at higher doses.

Precautions & Warnings

  • Paliperidone requires careful monitoring and specific precautions.
  • Pregnancy: safety not established; use only if benefits outweigh risks.
  • Breastfeeding: unknown; consider potential infant exposure.
  • Elderly: monitor for orthostatic hypotension and increased sedation.
  • Cardiovascular: assess for QT prolongation and hypotensive episodes.
  • Metabolic: monitor weight, glucose, and lipid levels.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Paliperidone can interact with other medicines, necessitating vigilance.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may increase plasma concentrations.
  • QT‑prolonging agents: additive risk of arrhythmia.
  • Alpha‑adrenergic antagonists: may enhance hypotensive effect.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may worsen cognitive side effects.
  • Concomitant antipsychotics: increase risk of extrapyramidal symptoms.
  • CNS depressants (e.g., benzodiazepines): may enhance sedation.

Frequently Asked Questions

Mopetia, containing the active ingredient paliperidone, is prescribed for the management of schizophrenia and schizoaffective disorder in adult patients. It helps reduce psychotic symptoms, stabilise mood, and improve overall functional outcomes as part of a comprehensive treatment plan.

Paliperidone works by blocking dopamine D2 receptors and serotonin 5‑HT2A receptors in the brain. This dual antagonism balances dopaminergic and serotonergic activity, decreasing the over‑activity that contributes to psychotic symptoms while also addressing negative and mood‑related aspects of the disorders.

The appropriate dose of Mopetia is determined by the prescribing clinician based on the individual’s clinical condition, response, and tolerability. Dosage regimens are not publicly disclosed and should be obtained from the treating healthcare professional.

Safety data for paliperidone in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies the potential risk to the fetus or infant. Clinicians should discuss individual circumstances and consider alternative therapies when appropriate.

To order Mopetia, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Mopetia (paliperidone) is a metabolite of risperidone and shares a similar receptor profile, but its long‑acting injectable form provides more consistent plasma levels and improved adherence compared with many oral atypical antipsychotics. Compared with other injectables, it offers a convenient dosing interval and a well‑characterised safety profile.

Mopetia should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability and ensure proper handling during transport.

Mopetia is administered as an intramuscular injection by a qualified healthcare professional. The injection is typically given in the gluteal or deltoid muscle, following aseptic technique, and the dosing schedule is defined by the prescribing clinician.

The most serious adverse reactions to monitor include neuroleptic malignant syndrome (characterised by fever, rigidity, and autonomic instability), tardive dyskinesia (potentially irreversible involuntary movements), and seizures, especially at higher doses or in predisposed individuals.

Mopetia is contraindicated in patients with known hypersensitivity to paliperidone or any component of the formulation. It should also be avoided in individuals with severe central nervous system depression, uncontrolled cardiovascular conditions, or those taking medications that significantly prolong the QT interval without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.