Product image of Morfex (Flurazepam Hydrochloride) supplied by GNH India

Morfex

Active Ingredient:
Flurazepam Hydrochloride
Origin:
EU

Morfex (Flurazepam Hydrochloride)

Flurazepam, the active ingredient in Morfex, is a benzodiazepine presented as an oral tablet for oral use. It acts as a sedative‑hypnotic and is prescribed primarily for the short‑term management of insomnia in adult patients who experience difficulty falling or staying asleep.

GNH India supplies Morfex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from consistent product availability and regulatory support across multiple markets.

Manufacturer / TM Owner

Tecnifar, Indústria Técnica Farmacêutica, Sa

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Indications & Clinical Uses

  • Flurazepam is a benzodiazepine that acts on the central nervous system to promote sleep.
  • Insomnia (sleep onset): reduces the time required to fall asleep.
  • Insomnia (sleep maintenance): decreases the number of nocturnal awakenings.
  • Insomnia (overall sleep quality): increases total sleep time and improves perceived sleep quality.

How It Works

  • Flurazepam binds to the benzodiazepine site on the GABA‑A receptor complex, acting as a positive allosteric modulator. This enhances the frequency of chloride channel opening in response to GABA, increasing neuronal inhibition and producing a calming, sedative effect that facilitates sleep initiation and maintenance.

Side Effects

Flurazepam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Drowsiness
  • Fatigue
  • Dizziness
  • Memory impairment
  • Ataxia
  • Headache

Serious or Rare Side Effects

  • Respiratory depression
  • Severe allergic reaction (e.g., rash, angioedema)
  • Paradoxical agitation or aggression
  • Depression or suicidal thoughts
  • Dependence and withdrawal syndrome
  • Hepatic dysfunction

Precautions & Warnings

When prescribing or dispensing Flurazepam, consider the following safety measures.

  • Assess renal and hepatic function: adjust use in severe impairment.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent withdrawal.
  • Use caution in elderly patients: increased sensitivity to sedation and falls.
  • Avoid concurrent CNS depressants: risk of enhanced sedation and respiratory depression.
  • Pregnancy and lactation: consult a healthcare provider before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Flurazepam can interact with several other medicines, requiring attention to avoid harmful effects.

Major Interactions (Avoid)

  • Alcohol: additive central nervous system depression.
  • Opioids: increased risk of respiratory depression.
  • Other benzodiazepines: cumulative sedation and profound CNS depression.

Moderate Interactions (Monitor Closely)

  • SSRIs or other antidepressants: may increase sedation.
  • Antihistamines: additive drowsiness.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise flurazepam plasma concentrations.

Frequently Asked Questions

Morfex contains flurazepam, a benzodiazepine prescribed for the short‑term treatment of insomnia in adults. It helps patients fall asleep faster, stay asleep longer, and improve overall sleep quality when used under medical supervision.

Flurazepam binds to the benzodiazepine site on the GABA‑A receptor, enhancing the inhibitory effect of the neurotransmitter GABA. This increased chloride influx hyperpolarizes neurons, producing a calming effect that facilitates sleep initiation and maintenance.

The appropriate dose of Morfex is determined by the prescribing clinician based on the patient’s age, medical condition, and response to therapy. Dosage adjustments may be needed for renal or hepatic impairment, and the medication should be taken exactly as directed.

Safety of flurazepam in pregnancy or while breastfeeding has not been definitively established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using Morfex.

To request Morfex, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Morfex (flurazepam) belongs to the benzodiazepine class, offering rapid onset of sleep but with a risk of dependence and next‑day sedation. Non‑benzodiazepine hypnotics (e.g., zolpidem) have a shorter half‑life and lower dependence potential, while melatonin receptor agonists act via a different pathway and are generally considered safer for long‑term use.

Morfex should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat, and direct sunlight to maintain potency and stability throughout its shelf life.

Morfex is taken orally, usually once nightly before bedtime. The tablet should be swallowed whole with a glass of water and not chewed or crushed. Patients should follow the prescribing clinician’s instructions regarding timing and any required dose adjustments.

Serious risks include respiratory depression, severe allergic reactions, paradoxical agitation, depression or suicidal thoughts, and the potential for physical dependence and withdrawal symptoms after prolonged use. Immediate medical attention is required if any of these events occur.

Morfex is contraindicated in individuals with known hypersensitivity to flurazepam or other benzodiazepines, severe respiratory insufficiency, acute narrow‑angle glaucoma, and in patients who are currently abusing alcohol or other CNS depressants. It should also be used with extreme caution in the elderly and in those with significant hepatic or renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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