Product image of Morphini Sulfas Spinal Wzf (Morphine Sulfate) supplied by GNH India

Morphini Sulfas Spinal Wzf

Active Ingredient:
Morphine Sulfate
Origin:
EU

Morphini Sulfas Spinal Wzf (Morphine Sulfate)

Morphine sulfate, the active ingredient in Morphini Sulfas Spinal Wzf, is an opioid analgesic presented as a sterile solution for epidural, intrathecal, and intravenous use. It is employed to treat severe acute pain, chronic cancer pain, and postoperative pain in adult patients requiring potent analgesia.

GNH India supplies Morphini Sulfas Spinal Wzf as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and oncology centres worldwide, with full regulatory compliance and quality assurance. The product meets EU pharmacopoeial standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Morphine sulfate, an opioid analgesic administered via epidural, intrathecal, or intravenous routes, is used to manage severe pain conditions.

  • Severe acute pain: provides rapid and potent analgesia for patients experiencing intense, short‑term pain.
  • Chronic cancer pain: helps control persistent pain associated with malignant disease, improving quality of life.
  • Postoperative pain: reduces pain after surgical procedures, facilitating recovery and mobilization.

How It Works

  • Morphine sulfate exerts its analgesic effect by binding to mu‑opioid receptors in the central nervous system. This agonist action inhibits the release of excitatory neurotransmitters, decreases neuronal excitability, and modulates pain signaling pathways in the spinal cord and brain, resulting in reduced perception of pain and increased pain tolerance. The activation also triggers downstream G‑protein signaling that closes calcium channels and opens potassium channels, further dampening neuronal firing.

Side Effects

Morphine sulfate may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Constipation
  • Drowsiness
  • Dizziness

Serious or Rare Side Effects

  • Respiratory depression
  • Severe hypotension
  • Anaphylactic reaction
  • Seizures

Precautions & Warnings

When prescribing Morphini Sulfas Spinal Wzf, clinicians should consider several safety measures.

  • Assess respiratory function: monitor for depression especially after dose adjustments.
  • Evaluate renal and hepatic function: adjust therapy if significant impairment is present.
  • Check for hypersensitivity: avoid use in patients with known allergy to morphine or opioid excipients.
  • Use caution in the elderly: increased sensitivity to central nervous system effects may occur.
  • Pregnancy Category C: weigh potential benefits against risks before prescribing.
  • Store below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Morphini Sulfas Spinal Wzf can interact with several medication classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Respiratory depressants (e.g., benzodiazepines, barbiturates): may cause profound respiratory depression.
  • MAO inhibitors: risk of severe hypertension or serotonin syndrome.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): increase morphine plasma concentrations.
  • CNS depressants (e.g., alcohol, antihistamines): additive sedation and respiratory effects.
  • Opioid antagonists (e.g., naloxone) administered concurrently: may reverse analgesic effect.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce morphine efficacy.
  • Diuretics: may enhance hypotensive effect of morphine.
  • Anticholinergic agents: may worsen constipation.

Frequently Asked Questions

Morphini Sulfas Spinal Wzf contains morphine sulfate and is indicated for the management of severe acute pain, chronic cancer‑related pain, and postoperative pain. It is administered by epidural, intrathecal, or intravenous injection to provide potent analgesia in patients who require strong opioid therapy.

Morphine sulfate works by binding to mu‑opioid receptors in the central nervous system. This binding inhibits the release of excitatory neurotransmitters, reduces neuronal excitability, and modulates pain pathways in the spinal cord and brain, leading to decreased perception of pain and increased pain tolerance.

The appropriate dose of Morphini Sulfas Spinal Wzf is determined by the prescribing clinician based on the patient’s pain severity, prior opioid exposure, route of administration, and individual clinical factors such as age, organ function, and concomitant medications. No fixed regimen is provided in public documentation.

Morphini Sulfas Spinal Wzf is classified as Pregnancy Category C, meaning risk cannot be ruled out. It should only be used during pregnancy or lactation when the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Morphini Sulfas Spinal Wzf delivers morphine sulfate, a benchmark mu‑opioid receptor agonist. Compared with newer synthetic opioids, morphine has a well‑characterized efficacy and safety profile, but may have a higher incidence of certain side effects such as histamine‑mediated flushing. Choice of agent depends on clinical context, patient response, and regulatory considerations.

Store Morphini Sulfas Spinal Wzf below 25 °C in its original packaging. Protect the product from moisture, direct sunlight, and physical damage. Do not freeze the solution, and ensure the container remains sealed until use to maintain sterility.

The product is supplied as a sterile solution intended for injection. It may be administered epidurally, intrathecally, or intravenously by a qualified healthcare professional, following aseptic technique and appropriate dosing calculations as ordered by the prescriber.

The most serious risks include respiratory depression, severe hypotension, anaphylactic reactions, adrenal insufficiency, and seizures. Patients should be closely monitored for signs of respiratory compromise, cardiovascular instability, and any allergic manifestations, especially during initiation or dose escalation.

Morphini Sulfas Spinal Wzf should be avoided in individuals with known hypersensitivity to morphine or any component of the formulation, in patients with severe respiratory depression not adequately treated, and in those for whom opioid therapy is contraindicated, such as certain cases of acute asthma or paralytic ileus.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.