Motifene (Diclofenac Sodium)

Diclofenac sodium blocks the activity of cyclooxygenase enzymes (COX‑1 and COX‑2), which are essential for producing prostaglandins. By reducing prostaglandin levels, it diminishes inflammation, lowers pain signals, and helps control fever.

The specific dose of Motifene is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions precisely.

Safety data for diclofenac in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

Enquiries for Motifene can be submitted through the product page on gnhindia.com. Provide the required quantity and institutional details. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then replies with pricing, availability, shipping options and any necessary import documentation.

Motifene (diclofenac) offers potent anti‑inflammatory and analgesic effects comparable to ibuprofen or naproxen, but it may have a higher risk of gastrointestinal and cardiovascular adverse events at equivalent doses. Choice of NSAID should consider individual risk factors, comorbidities and physician preference.

Motifene should be stored at ambient temperature below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Do not store in a location where temperature may exceed the recommended range.

Motifene is taken orally, usually with a full glass of water. It may be taken with food or milk to reduce gastrointestinal discomfort, unless the prescriber advises otherwise.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe liver injury, acute kidney failure, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms like black stools, jaundice, sudden swelling, or severe rash.

Motifene is contraindicated in individuals with known hypersensitivity to diclofenac or other NSAIDs, active peptic ulcer disease, severe heart failure, significant renal or hepatic impairment, and in patients who have experienced a recent myocardial infarction or stroke unless specifically directed by a physician.