Motion (Dienogest, Ethinylestradiol)

Motion is a combined oral contraceptive that acts on the hypothalamic‑pituitary‑ovarian axis to prevent pregnancy and normalize menstrual bleeding.

• Contraception: provides reliable birth control by inhibiting ovulation and altering cervical mucus.
• Menstrual cycle regulation: reduces irregular bleeding and stabilises cycle length.
• Endometriosis‑related pain: alleviates pelvic pain associated with endometriosis through hormonal suppression.

• Ethinylestradiol and Dienogest work together to suppress the mid‑cycle surge of luteinising hormone and follicle‑stimulating hormone, thereby preventing ovulation. Ethinylestradiol stabilises the endometrium, while Dienogest provides progestogenic activity that thickens cervical mucus and further impedes implantation.

Side effects may vary in frequency and severity.

Common Side Effects

• Nausea: mild to moderate upset stomach.
• Headache: tension‑type or migraine‑like.
• Breast tenderness: temporary swelling or discomfort.
• Weight gain: modest fluid retention.
• Mood changes: irritability or mild depression.
• Spotting: breakthrough bleeding, especially in early cycles.

Serious or Rare Side Effects

• Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.
• Hypertension: sudden increase in blood pressure.
• Liver dysfunction: jaundice or abnormal liver enzymes.
• Allergic reaction: rash, itching, swelling, or anaphylaxis.
• Visual disturbances: blurred vision or retinal vein occlusion.
• Severe abdominal pain: possible gallbladder disease.

Before prescribing Motion, clinicians should assess individual risk factors and contraindications.

• Smoking status: avoid use in women over 35 who smoke.
• Cardiovascular disease: contraindicated in patients with a history of thromboembolic events.
• Liver disease: use with caution in hepatic impairment.
• Migraine with aura: avoid due to increased stroke risk.
• Breast cancer history: contraindicated in active or past breast malignancy.
• Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct light.

Motion can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

• Anticoagulants (e.g., warfarin): may reduce anticoagulant effect.
• Antiepileptics (e.g., carbamazepine, phenytoin): can lower contraceptive hormone levels.
• Rifampicin: induces metabolism, decreasing contraceptive effectiveness.

Moderate Interactions (Monitor Closely)

• Antidepressants (SSRIs, SNRIs): may increase risk of serotonin syndrome.
• Antibiotics (e.g., tetracycline): occasional reduction in contraceptive efficacy.
• Herbal supplements (St. John’s wort): may modestly decrease hormone levels.