Product image of Motsalon (Sodium Selenite) supplied by GNH India

Motsalon

Active Ingredient:
Sodium Selenite
Origin:
EU

Motsalon (Sodium Selenite)

Sodium selenite, the active ingredient in Motsalon, is a selenium supplement presented as an oral formulation for oral use. It is used to correct selenium deficiency and to support antioxidant defenses and thyroid hormone metabolism in adult patients.

GNH India supplies Motsalon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, sourcing the product from EU manufacturers and adhering to quality standards. The product meets EU regulatory requirements and is available over the counter.

Manufacturer / TM Owner

Verisfield S.M.S.A

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Indications & Clinical Uses

Motsalon (sodium selenite) is used to address conditions related to selenium deficiency and its role in antioxidant and thyroid pathways.

  • Selenium deficiency: restores normal selenium levels and supports selenoprotein synthesis.
  • Oxidative stress: enhances antioxidant capacity by contributing to glutathione peroxidase activity.
  • Thyroid health support: aids conversion of thyroid hormones by providing a necessary cofactor for deiodinases.

How It Works

  • Sodium selenite is absorbed in the gastrointestinal tract and reduced to selenide, which is incorporated into selenocysteine during protein synthesis. The resulting selenoproteins, such as glutathione peroxidases and thioredoxin reductases, function as antioxidants, protecting cells from oxidative damage. Selenium also serves as a cofactor for iodothyronine deiodinases, enzymes that convert thyroxine (T4) to the active hormone triiodothyronine (T3), thereby influencing thyroid hormone metabolism.

Side Effects

Oral sodium selenite may be associated with a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Metallic taste: transient alteration in taste perception.
  • Diarrhea: loose stools.
  • Headache: mild to moderate.
  • Fatigue: general tiredness.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling.
  • Stevens‑Johnson syndrome: severe skin eruption.
  • Anaphylaxis: rapid onset of breathing difficulty and hypotension.
  • Severe respiratory distress: rare pulmonary edema.

Precautions & Warnings

When using Motsalon, certain precautions should be observed to ensure safety and effectiveness.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: use only if benefits outweigh potential risks.
  • Renal impairment: monitor selenium status and adjust dosage as needed.
  • Drug interactions: review concomitant medications for possible selenium interactions.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Sodium selenite can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Antithyroid drugs (e.g., propylthiouracil): may diminish therapeutic effect of selenium on thyroid function.
  • High-dose vitamin C supplements: can reduce selenium absorption.
  • Anticoagulants (e.g., warfarin): selenium may potentiate anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely)

  • Levothyroxine: concurrent use may require thyroid function monitoring.
  • Chemotherapy agents (e.g., cisplatin): selenium may affect drug toxicity profile.
  • Statins: monitor for muscle‑related side effects.

Frequently Asked Questions

Motsalon contains sodium selenite, a form of the trace element selenium. It is used to treat or prevent selenium deficiency, to support the body's antioxidant defenses, and to aid normal thyroid hormone metabolism in adults.

After oral absorption, sodium selenite is reduced to selenide, which is incorporated into selenocysteine during protein synthesis. This creates selenoproteins such as glutathione peroxidase that protect cells from oxidative damage, and it also serves as a cofactor for enzymes that activate thyroid hormones.

The appropriate dose of Motsalon is determined by a qualified healthcare professional based on the individual’s clinical condition, age, weight, and laboratory results. Prescribers set the regimen to achieve optimal selenium status while avoiding excess.

Safety data for sodium selenite in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential benefits and risks with their healthcare provider before starting Motsalon.

To request Motsalon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Motsalon provides sodium selenite, an inorganic selenium source that is rapidly converted to bioavailable selenide. Compared with organic forms such as selenomethionine, sodium selenite may achieve higher plasma selenium levels more quickly, but the clinical choice depends on the therapeutic goal, patient tolerance and prescriber preference.

Store Motsalon at room temperature, below 25 °C, in its original packaging. Protect it from moisture, excessive heat and direct sunlight. Keep the container tightly closed and out of reach of children.

Motsalon is taken orally, usually with water. It may be taken with or without food, unless the prescribing clinician advises otherwise. The exact timing and frequency should follow the instructions given by the prescribing healthcare professional.

Serious adverse reactions, although rare, include severe allergic responses such as rash, swelling, Stevens‑Johnson syndrome, anaphylaxis, and respiratory distress. Any signs of a severe reaction require immediate medical attention.

Motsalon should be avoided in individuals with known hypersensitivity to sodium selenite or other selenium compounds, and in patients with uncontrolled thyroid disorders unless closely monitored. Persons with severe renal impairment should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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