Product image of MOUNJARO 2.5mg (Tirzepatide) 2.5mgx0.5ml PFS supplied by GNH India

MOUNJARO 2.5mg

Active Ingredient:
Tirzepatide
Form:
PFS
Brand:
MOUNJARO
Origin:
USA

MOUNJARO 2.5mg (Tirzepatide PFS) 2.5mgx0.5ml

Tirzepatide, the active ingredient in Mounjaro, is a GIP/GLP-1 receptor agonist presented as a 2.5mg/0.5ml pre-filled syringe for subcutaneous use. It is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.

GNH India supplies Mounjaro as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

2.5mgx0.5ml

Pack Size

4s

Storage

2-8°

Manufacturer / TM Owner

LILLY ELI & CO

1
Pack/s
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Indications & Clinical Uses

Mounjaro is a GIP/GLP-1 receptor agonist used in the management of type 2 diabetes mellitus. It is indicated for:

  • Type 2 diabetes mellitus: Improves glycemic control in adults and pediatric patients 10 years of age and older as an adjunct to diet and exercise.
  • Obesity: While not its primary indication, some patients may experience weight loss as a secondary effect.

How It Works

  • Tirzepatide, the active ingredient in Mounjaro, activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. This dual action enhances insulin secretion, suppresses glucagon release, and slows gastric emptying, thereby helping to regulate blood sugar levels in patients with type 2 diabetes mellitus.

Side Effects

Mounjaro may cause various side effects, ranging from common to serious or rare.

Common Side Effects

  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation
  • Injection site reactions
  • Fatigue
  • Dizziness

Serious or Rare Side Effects

  • Pancreatitis: Severe abdominal pain that may radiate to the back
  • Hypoglycemia: Low blood sugar levels, especially when used with other antidiabetic medications
  • Kidney problems: Dehydration leading to kidney issues
  • Allergic reactions: Swelling of the face, lips, tongue, or throat, difficulty breathing, severe rash, or itching
  • Thyroid tumors: Symptoms such as a lump or swelling in the neck, hoarseness, or trouble swallowing

Precautions & Warnings

Mounjaro should be used with caution and certain precautions should be observed:

  • Avoid use in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Monitor for symptoms of pancreatitis, such as severe abdominal pain
  • Be cautious when using with other medications that may cause hypoglycemia
  • Inform healthcare providers of any symptoms of thyroid tumors, such as a lump or swelling in the neck
  • Avoid use in patients with known serious hypersensitivity to tirzepatide or any of the excipients in Mounjaro
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Mounjaro may interact with other medications, which can affect its efficacy or increase the risk of side effects.

Major Interactions (Avoid)

  • Insulin: Increased risk of hypoglycemia when used together
  • Other antidiabetic medications: May enhance the glucose-lowering effects, increasing the risk of hypoglycemia

Moderate Interactions (Monitor Closely)

  • Oral medications: Mounjaro may slow gastric emptying, affecting the absorption of oral medications
  • Diuretics: May increase the risk of dehydration and kidney problems
  • Corticosteroids: May reduce the glucose-lowering effects of Mounjaro

Frequently Asked Questions

Mounjaro is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. It is a GIP/GLP-1 receptor agonist that helps regulate blood sugar levels by enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptying.

Tirzepatide, the active ingredient in Mounjaro, activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. This dual action enhances insulin secretion, suppresses glucagon release, and slows gastric emptying, thereby helping to regulate blood sugar levels in patients with type 2 diabetes mellitus.

The usual starting dose of Mounjaro is 2.5 mg once weekly. The dose can be increased gradually based on the patient's glycemic control and tolerability, as determined by the prescribing healthcare provider. The maximum recommended dose is 15 mg once weekly for adults and 10 mg once weekly for pediatric patients.

The safety of Mounjaro during pregnancy or breastfeeding has not been established. It is important to consult with a healthcare provider to discuss the potential risks and benefits before using Mounjaro in these situations. Pregnancy should be avoided during treatment with Mounjaro unless clearly necessary.

To order Mounjaro from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

Mounjaro is a dual GIP/GLP-1 receptor agonist, which distinguishes it from other diabetes medications that may target only one of these receptors or use different mechanisms. Its dual action can provide more comprehensive glycemic control and may offer additional benefits such as weight loss, though it is not approved specifically for weight management.

Mounjaro should be stored at 2-8°C, refrigerated, and protected from light. It should not be frozen or shaken. Always follow the storage instructions provided with the medication to ensure its efficacy and safety.

Mounjaro is administered as a subcutaneous injection once weekly. The pre-filled single-dose pen makes it convenient for self-administration or administration by a healthcare provider. It is important to follow the administration instructions provided with the medication.

The most serious risks to watch for with Mounjaro include symptoms of pancreatitis (severe abdominal pain), hypoglycemia (low blood sugar), kidney problems (dehydration), allergic reactions (swelling, difficulty breathing), and thyroid tumors (lump or swelling in the neck, hoarseness). Patients should report any of these symptoms to their healthcare provider immediately.

Mounjaro should not be used by patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). It is also contraindicated in patients with known serious hypersensitivity to tirzepatide or any of the excipients in Mounjaro. Always consult with a healthcare provider to determine if Mounjaro is appropriate for you.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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