Product image of Movalis (Meloxicam) supplied by GNH India

Movalis

Active Ingredient:
Meloxicam
Origin:
EU

Movalis (Meloxicam)

Meloxicam, the active ingredient in Movalis, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular use. It is indicated for the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and acute pain in adult patients.

GNH India supplies Movalis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance. Our distribution network ensures timely delivery across Europe, Asia, Africa and the Americas, adhering to cold‑chain requirements for injectable products.

Manufacturer / TM Owner

Boehringer Ingelheim International Gmbh

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Indications & Clinical Uses

Movalis (meloxicam) is used to treat inflammatory musculoskeletal conditions by reducing pain and swelling.

  • Rheumatoid arthritis: reduces joint inflammation, pain and improves functional ability.
  • Osteoarthritis: alleviates chronic joint pain and enhances mobility.
  • Ankylosing spondylitis: decreases spinal inflammation and stiffness, improving posture.
  • Acute pain: provides short‑term relief of moderate to severe pain.

How It Works

  • Meloxicam selectively inhibits the cyclooxygenase‑2 (COX‑2) enzyme, which converts arachidonic acid to prostaglandins that mediate inflammation, pain and fever. By preferentially blocking COX‑2 while sparing COX‑1, meloxicam reduces prostaglandin synthesis at sites of inflammation, producing anti‑inflammatory, analgesic and antipyretic effects with a lower risk of gastrointestinal mucosal injury compared with non‑selective NSAIDs.

Side Effects

Common and serious adverse reactions have been reported with meloxicam injection.

Common Side Effects

  • Injection site pain: mild to moderate discomfort at the site of administration.
  • Headache: transient headache occurring shortly after dosing.
  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Dizziness: occasional light‑headedness or vertigo.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines.
  • Cardiovascular events: increased risk of heart attack or stroke, especially in high‑risk patients.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Renal impairment: acute kidney injury or worsening of chronic renal disease.

Precautions & Warnings

Before prescribing Movalis, clinicians should consider several precautionary measures to minimise risk.

  • Renal function: assess baseline kidney function and monitor during therapy.
  • Cardiovascular risk: use cautiously in patients with history of heart disease or stroke.
  • Gastrointestinal risk: avoid in individuals with active peptic ulcer disease or prior GI bleeding.
  • Pregnancy and lactation: contraindicated unless benefits outweigh potential risks, as safety data are limited.
  • Concomitant medications: review for drugs that increase bleeding or renal toxicity.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Meloxicam may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity and renal impairment.
  • High‑dose aspirin: increased bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated patients.
  • Diuretics: potential for decreased renal perfusion and electrolyte disturbances.
  • Lithium: meloxicam can raise lithium serum concentrations, requiring monitoring.

Frequently Asked Questions

Movalis contains meloxicam, an NSAID indicated for the treatment of inflammatory joint disorders such as rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, as well as for short‑term relief of moderate to severe acute pain. The medication works by reducing inflammation and pain in the affected tissues.

Meloxicam exerts its effect by selectively inhibiting the cyclooxygenase‑2 (COX‑2) enzyme, which is responsible for producing prostaglandins that drive inflammation, pain and fever. By sparing COX‑1, meloxicam lowers prostaglandin levels at sites of inflammation while preserving protective prostaglandins in the stomach and kidneys, providing anti‑inflammatory and analgesic benefits.

The dose of Movalis is determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms, renal and hepatic function, and other individual factors. The prescriber will select the appropriate strength, frequency and duration of treatment in accordance with local prescribing guidelines and the product label.

Safety data for meloxicam in pregnancy and lactation are limited, and the product is generally classified as contraindicated or to be used only when the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To order Movalis, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including cold‑chain handling if required) and any necessary import documentation.

Movalis (meloxicam) is a selective COX‑2 inhibitor, which typically offers a lower incidence of gastrointestinal irritation compared with non‑selective NSAIDs such as ibuprofen or diclofenac. However, it shares class‑related risks of cardiovascular events and renal impairment, especially at higher doses or in patients with pre‑existing risk factors.

Movalis injectable solution should be stored at 2‑8 °C (refrigerated). Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the product. If refrigeration is temporarily unavailable, the product may be kept at controlled room temperature for a limited period as indicated in the product label.

Movalis is supplied as an injectable solution for intramuscular injection. Administration must be performed by a qualified healthcare professional using aseptic technique. The injection site is typically the gluteal or deltoid muscle, and the volume administered follows the prescriber’s instructions based on the selected dose.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as myocardial infarction or stroke, and renal impairment that can lead to acute kidney injury. Patients with a history of peptic ulcer disease, heart disease, or compromised kidney function should be closely monitored, and any signs of severe adverse reactions require immediate medical attention.

Movalis should be avoided in individuals with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal ulceration or bleeding, severe renal or hepatic impairment, and patients with established cardiovascular disease who are at high risk for thrombotic events. It is also contraindicated in patients who have had a recent coronary artery bypass graft (CABG) surgery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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