Product image of Movalis (Meloxicam) supplied by GNH India

Movalis

Active Ingredient:
Meloxicam
Origin:
EU

Movalis (Meloxicam)

Meloxicam, the active ingredient in Movalis, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and other acute pain conditions.

GNH India supplies Movalis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Boehringer Ingelheim International Gmbh

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Indications & Clinical Uses

  • Movalis, a meloxicam‑based NSAID, acts on inflammatory pathways to manage several musculoskeletal disorders.
  • Osteoarthritis: reduces joint pain and swelling, improving mobility.
  • Rheumatoid arthritis: alleviates chronic inflammation and joint damage.
  • Ankylosing spondylitis: eases spinal pain and stiffness.
  • Acute pain: provides rapid relief for short‑term painful episodes.

How It Works

  • Meloxicam selectively inhibits cyclooxygenase‑2 (COX‑2) enzymes, with lesser effect on COX‑1, leading to decreased synthesis of prostaglandins that mediate inflammation, pain, and fever. By reducing prostaglandin production at sites of inflammation, it diminishes the inflammatory response while preserving gastric protective prostaglandins to a greater extent than non‑selective NSAIDs.

Side Effects

Common Side Effects

  • Gastrointestinal discomfort such as dyspepsia or nausea.
  • Headache or dizziness.
  • Mild elevation of liver enzymes.
  • Edema or fluid retention.
  • Skin rash or pruritus.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hepatic injury.
  • Renal impairment or failure.
  • Cardiovascular events such as myocardial infarction.
  • Severe skin reactions like Stevens‑Johnson syndrome.
  • Anaphylaxis or other hypersensitivity reactions.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess renal and hepatic function: adjust use if impairment is present.
  • Evaluate cardiovascular risk: use cautiously in patients with heart disease.
  • Monitor for gastrointestinal ulceration, especially in high‑risk individuals.
  • Avoid use in patients with known hypersensitivity to meloxicam or other NSAIDs.
  • Use during pregnancy only if clearly needed; category C indicates risk cannot be ruled out.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Meloxicam may interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may enhance nephrotoxic effects.
  • Lithium: meloxicam can raise lithium serum levels.
  • Methotrexate: potential for increased toxicity.

Frequently Asked Questions

Movalis contains meloxicam, an NSAID that is prescribed to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other acute painful conditions. It helps improve joint function and reduces swelling in these musculoskeletal disorders.

Meloxicam works by selectively inhibiting the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins that cause inflammation, pain, and fever. By targeting COX‑2 more than COX‑1, it provides anti‑inflammatory effects while sparing some protective gastric prostaglandins.

The appropriate dose of Movalis is determined by the prescribing healthcare professional based on the individual’s medical condition, age, renal and hepatic function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Movalis is classified as Pregnancy Category C, meaning risk cannot be ruled out and it should only be used if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should consult their physician before using the product.

To order Movalis, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with non‑selective NSAIDs, meloxicam offers a higher degree of COX‑2 selectivity, which may result in a lower incidence of gastrointestinal irritation while still providing effective anti‑inflammatory and analgesic action. However, cardiovascular and renal risks remain similar to other NSAIDs and must be monitored.

Movalis tablets should be stored at ambient temperature below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiration date printed on the label.

Movalis is taken orally, usually with a glass of water. It can be taken with or without food, although taking it with food may reduce occasional stomach upset. The exact administration schedule is set by the prescribing clinician.

Serious risks associated with Movalis include gastrointestinal bleeding or ulceration, severe liver injury, renal failure, cardiovascular events such as heart attack or stroke, and rare but life‑threatening skin reactions. Patients should seek immediate medical attention if they experience symptoms like black stools, severe abdominal pain, jaundice, sudden swelling, or rash.

Movalis should be avoided in individuals with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal ulceration, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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