Product image of Movicol Chokolade (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol Chokolade

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol Chokolade (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Movicol Chokolade, is an osmotic laxative presented as an oral solution for oral administration. It works by increasing intestinal water content, facilitating the passage of stool, and is indicated for the relief of constipation and fecal impaction in both adult and pediatric patients under medical supervision.

GNH India supplies Movicol Chokolade as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Norgine Healthcare B.V.

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Indications & Clinical Uses

Movicol, an osmotic laxative, is used to manage conditions involving reduced bowel motility.

  • Constipation: softens stool and promotes regular bowel movements.
  • Fecal impaction: helps break down hardened stool to relieve blockage.
  • Bowel preparation for colonoscopy: retains water in the lumen to cleanse the colon before diagnostic procedures.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is poorly absorbed from the gastrointestinal tract. It creates an osmotic gradient that draws water into the intestinal lumen, increasing stool water content and volume, which stimulates peristalsis and facilitates the passage of feces without stimulating intestinal secretions directly.

Side Effects

Common Side Effects

  • Nausea: mild to moderate feeling of sickness.
  • Abdominal bloating: sensation of fullness or swelling.
  • Flatulence: increased intestinal gas.
  • Abdominal pain or cramps: discomfort in the stomach area.
  • Diarrhoea: loose or watery stools.
  • Electrolyte imbalance: mild changes in sodium or potassium levels.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body fluids.
  • Severe electrolyte disturbances: significant hypo‑ or hyper‑natremia or hyper‑kalemia.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: persistent or worsening pain.
  • Blood in stool: presence of visible blood.
  • Acute renal failure: sudden loss of kidney function in susceptible individuals.

Precautions & Warnings

Before using Movicol, consider the following precautions:

  • Renal function assessment: evaluate kidney health to avoid fluid overload.
  • Electrolyte monitoring: check serum sodium and potassium levels regularly.
  • Bowel obstruction: avoid use in patients with known mechanical obstruction.
  • Hypersensitivity: discontinue if allergic reactions occur.
  • Elderly patients: start with lower doses and monitor tolerance.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Movicol may interact with other medicines as follows:

Major Interactions (Avoid)

  • Concomitant osmotic laxatives: risk of excessive fluid loss and electrolyte imbalance.
  • Loop diuretics: may amplify dehydration and electrolyte disturbances.
  • Mineralocorticoids (e.g., fludrocortisone): can worsen sodium retention issues.

Moderate Interactions (Monitor Closely)

  • Antacids containing magnesium: may increase gastrointestinal side effects.
  • NSAIDs: potential for renal function compromise when combined.
  • ACE inhibitors or ARBs: monitor blood pressure and renal parameters due to possible additive effects on electrolytes.

Frequently Asked Questions

Movicol Chokolade is an oral solution containing macrogol 3350, used primarily to relieve constipation and to treat fecal impaction. It works by increasing the water content of stool, making bowel movements easier and more regular under medical supervision.

Macrogol 3350 is a large polyethylene glycol polymer that is minimally absorbed in the gut. It creates an osmotic gradient that draws water into the intestinal lumen, softening stool and stimulating peristalsis, which facilitates the passage of feces without directly stimulating intestinal secretions.

The dose of Movicol Chokolade is individualized by a prescriber based on the patient’s age, weight, severity of constipation, and clinical response. Healthcare professionals determine the appropriate volume and frequency to achieve the desired therapeutic effect.

Safety data for macrogol 3350 during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with stimulant laxatives, macrogol 3350 acts osmotically, providing a gentler, water‑based softening effect without stimulating intestinal muscles. This often results in fewer cramping side effects, making it a preferred option for chronic constipation or bowel preparation.

Store Movicol Chokolade at ambient temperature, below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging to maintain product stability.

Movicol Chokolade is taken orally. The prescribed volume of the solution is measured using the supplied measuring device and consumed with water, usually once daily or as directed by a healthcare professional.

Serious risks include severe dehydration, marked electrolyte disturbances (especially sodium and potassium), allergic reactions, and, in rare cases, acute renal failure. Patients should be monitored for signs of these conditions, particularly if they have underlying kidney disease or are taking interacting medications.

Movicol Chokolade should be avoided in individuals with known hypersensitivity to macrogol 3350 or any of its excipients, in patients with mechanical bowel obstruction, and in those with severe renal impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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