Product image of Movicol Liquid Orange Flavour 13.7g/25ml (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol Liquid Orange Flavour 13.7g/25ml

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol Liquid Orange Flavour 13.7g/25ml (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350 with electrolytes, the active ingredient in Movicol Liquid Orange Flavour, is an osmotic laxative presented as a 13.7 g/25 mL oral solution for oral administration. It is indicated for the relief of constipation and works by retaining water in the intestinal lumen, thereby softening stool and facilitating bowel movements in adults and children under medical supervision.

GNH India supplies Movicol Liquid Orange Flavour as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and healthcare providers worldwide through its global distribution network.

Manufacturer / TM Owner

Norgine Pharmaceuticals Limited

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Indications & Clinical Uses

  • Movicol (macrogol 3350 with electrolytes) is used to treat constipation, an intestinal motility disorder.
  • Constipation: provides symptomatic relief by softening stool and facilitating bowel movements.
  • Chronic constipation: helps maintain regularity in patients with long‑term difficulty passing stool.
  • Opioid‑induced constipation: counteracts reduced gastrointestinal motility caused by opioid therapy.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not systemically absorbed. It creates an osmotic gradient that retains water within the intestinal lumen, while the accompanying electrolytes maintain fluid balance. The increased intraluminal water softens feces and expands stool volume, stimulating peristalsis and promoting easier passage of bowel contents.

Side Effects

Common Side Effects

  • Abdominal bloating or distension.
  • Flatulence or increased gas.
  • Nausea or mild stomach discomfort.
  • Diarrhoea or loose stools.
  • Thirst or mild dehydration.
  • Electrolyte imbalance (mild sodium or potassium shifts).

Serious or Rare Side Effects

  • Severe dehydration leading to dizziness or fainting.
  • Acute abdominal pain or intestinal cramps.
  • Significant electrolyte disturbances such as hypernatremia or hyperkalemia.
  • Allergic reactions including rash, itching or swelling.
  • Severe diarrhoea causing electrolyte loss.

Precautions & Warnings

Before using Movicol, consider the following precautions:

  • Renal function assessment: ensure adequate kidney function before initiating therapy.
  • Electrolyte monitoring: check serum electrolytes, especially in patients at risk of imbalance.
  • Dehydration risk: avoid use in individuals with existing fluid loss or severe dehydration.
  • Intestinal obstruction: contraindicated in patients with known bowel blockage or perforation.
  • Elderly patients: start with lower doses and monitor tolerance closely.
  • Discontinuation: do not stop abruptly without medical advice if used long term.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Movicol may interact with other medicines as follows:

Major Interactions (Avoid)

  • Other osmotic laxatives (e.g., sodium phosphate): risk of severe electrolyte disturbances.
  • Loop diuretics (e.g., furosemide): may exacerbate fluid and electrolyte loss.
  • Lithium therapy: altered lithium clearance can increase toxicity risk.

Moderate Interactions (Monitor Closely)

  • Oral anticoagulants (e.g., warfarin): fluid shifts may affect plasma volume and INR stability.
  • ACE inhibitors or ARBs: monitor blood pressure and renal function due to possible volume changes.
  • Antacids containing magnesium or aluminum: may affect absorption of electrolytes from the solution.

Frequently Asked Questions

Movicol Liquid Orange Flavour is an oral solution containing macrogol 3350 with electrolytes that is used to relieve constipation. It works by increasing the water content in the intestines, softening stool and helping to restore regular bowel movements in adults and children as directed by a healthcare professional.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that remains in the gastrointestinal tract. It creates an osmotic gradient that draws water into the lumen, while the added electrolytes maintain fluid balance. The resulting increase in intestinal water softens the stool and stimulates peristalsis, facilitating easier passage.

The dose of Movicol Liquid Orange Flavour is individualized. A prescriber determines the appropriate volume based on the patient’s age, weight, severity of constipation and clinical response. The product is supplied as a measured oral solution that should be taken exactly as instructed by a qualified healthcare professional.

Safety data for Movicol during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers will evaluate the individual situation and may recommend alternative treatments when safer options are available.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Movicol belongs to the osmotic laxative class, which differs from stimulant laxatives that act on intestinal nerves. Compared with stimulant agents, macrogol‑based solutions tend to cause fewer cramping sensations and provide a gentler, water‑based softening effect. However, choice of therapy depends on the patient’s condition, tolerance and physician recommendation.

Store the oral solution at ambient temperature, preferably below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture and direct sunlight, and ensure the label remains legible. Do not freeze the product; discard any solution that appears discoloured or contains particles.

The product is taken orally. The measured dose is mixed with a specified amount of water (usually 125 mL) and consumed as a single drink. It can be taken with or without food, but patients should follow the prescriber’s instructions regarding timing and any required fluid intake.

Serious risks include severe dehydration, marked electrolyte disturbances (such as hypernatremia or hyperkalemia), and rare allergic reactions. Patients experiencing intense abdominal pain, persistent diarrhoea, dizziness, or signs of electrolyte imbalance should seek medical attention promptly.

Movicol should be avoided in individuals with known or suspected intestinal obstruction, perforation, severe dehydration, or significant renal impairment unless directed by a physician. Patients with hypersensitivity to macrogol or any of the electrolyte components should also refrain from using the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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