Product image of Movicol Plain (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol Plain

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol Plain (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Movicol Plain, is an osmotic laxative presented as a powder for solution for oral use. It treats constipation and occasional constipation in adults and children by softening stool and promoting regular bowel movements. The formulation also contains sodium hydrogen carbonate, potassium chloride and sodium chloride to help maintain electrolyte balance.

GNH India supplies Movicol Plain as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with consistent quality and regulatory compliance.

Manufacturer / TM Owner

Norgine Pharmaceuticals Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Movicol Plain is used as an osmotic laxative to relieve constipation and support regular bowel function.

  • Constipation: helps soften stool and increase frequency of bowel movements.
  • Occasional constipation: provides rapid relief of infrequent or mild constipation episodes.
  • Functional constipation: assists patients with chronic functional bowel disorders to achieve regularity.

How It Works

  • Macrogol 3350 creates an osmotic gradient in the intestinal lumen, drawing water into the bowel. The increased water content softens the fecal mass and expands the stool volume, which stimulates peristalsis and facilitates easier passage. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help preserve electrolyte balance while the osmotic effect promotes regular bowel movements.

Side Effects

Movicol Plain may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: mild sensation of unease in the stomach.
  • Diarrhoea: loose or watery stools.
  • Cramping: intermittent abdominal muscle pain.
  • Thirst: increased desire to drink fluids.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body fluids requiring medical attention.
  • Electrolyte imbalance: abnormal levels of sodium, potassium or chloride that may affect heart rhythm.
  • Allergic reaction: rash, itching, swelling or difficulty breathing indicating hypersensitivity.

Precautions & Warnings

Before using Movicol Plain, consider the following safety measures.

  • Renal impairment: adjust dose or avoid use in severe kidney disease.
  • Electrolyte disorders: monitor serum electrolytes in patients prone to imbalance.
  • Gastrointestinal obstruction: contraindicated in mechanical blockage of the intestines.
  • Chronic diarrhoea: avoid if the patient already has persistent loose stools.
  • Pediatric use: use only under medical supervision for children.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Movicol Plain can interact with other medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid)

  • Concurrent osmotic laxatives: may cause excessive fluid loss and electrolyte disturbances.
  • Potassium-sparing diuretics: increased risk of hyperkalaemia.
  • Lithium therapy: altered lithium plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: monitor electrolytes and renal function.
  • Antacids containing aluminium or magnesium: may affect absorption of the laxative.
  • Antihypertensive agents: watch for changes in blood pressure due to fluid shifts.

Frequently Asked Questions

Movicol Plain is an oral osmotic laxative indicated for the relief of constipation and occasional constipation. It works by softening stool and increasing bowel movement frequency, helping adults and children who experience difficulty passing stool to achieve regularity.

Macrogol 3350 is a high‑molecular‑weight polymer that remains largely unabsorbed in the gut. It retains water within the intestinal lumen, creating an osmotic gradient that softens feces and expands stool volume, which stimulates peristalsis and facilitates easier evacuation.

The dose of Movicol Plain is individualized by a healthcare professional based on the patient’s age, severity of constipation and clinical response. The prescriber determines the appropriate amount of powder to dissolve in water and the frequency of administration.

The pregnancy safety category for Movicol Plain is not definitively established. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their physician before using the product.

To order Movicol Plain, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Movicol Plain acts osmotically rather than stimulating intestinal nerves, resulting in a gentler, more gradual softening of stool. It is generally preferred for patients who need regular, long‑term bowel regulation, whereas stimulant agents are often reserved for short‑term or refractory cases.

Store Movicol Plain at ambient temperature, preferably below 25 °C. Keep the powder in its original, tightly sealed container, protect it from moisture and direct sunlight, and ensure it is out of reach of children.

The powder is dissolved in a specified volume of water, usually 125 ml to 250 ml, according to the prescriber’s instructions. The solution should be mixed thoroughly and consumed promptly after preparation. It is taken orally, with or without food, as directed.

Serious risks include severe dehydration, electrolyte imbalance (especially low sodium or potassium), and rare allergic reactions such as rash, swelling or breathing difficulty. Patients experiencing these symptoms should seek immediate medical attention.

Movicol Plain should be avoided in individuals with known hypersensitivity to any component, those with intestinal obstruction, severe renal impairment, or uncontrolled electrolyte disorders. It is also contraindicated in patients with acute abdominal conditions requiring urgent medical evaluation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT