Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350 is a high‑molecular‑weight polymer that is minimally absorbed in the gut. It creates an osmotic gradient that draws water into the intestinal lumen, softening the stool and expanding its volume. The added electrolytes help maintain fluid balance while the increased stool bulk stimulates peristalsis, resulting in a gentle laxative effect.

The dosage of Movicol is individualized by the prescribing healthcare professional based on the patient’s age, severity of constipation, and response to therapy. The prescriber determines the amount of powder to dissolve in water and the frequency of administration, which may be adjusted over time to achieve the desired bowel habit.

Safety data for Movicol in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk to the fetus or infant, and under medical supervision. Breastfeeding mothers should consult their physician, as the drug may be excreted in small amounts in breast milk.

To place an order, submit an enquiry on the Movicol product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Movicol provides a softer, non‑irritating effect by osmotically retaining water rather than stimulating intestinal muscles. It is generally better tolerated than bulk‑forming agents in patients who need rapid relief. However, it may be less effective for severe obstruction, where a stimulant or surgical approach may be required.

Movicol powder should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed when not in use. Do not freeze the product, and ensure that it is kept out of reach of children.

The powder is dissolved in a measured amount of water, usually 125 ml, and stirred until fully dissolved. The solution is then consumed immediately. The dosage volume and frequency are determined by the prescriber, and the patient should follow the specific instructions regarding mixing and timing relative to meals.

The most serious risks include severe dehydration, electrolyte imbalance (particularly low sodium or potassium), and rare allergic reactions that can cause rash, swelling or breathing difficulties. Patients experiencing persistent diarrhoea, dizziness, or signs of an allergic response should seek medical attention promptly.

Movicol is contraindicated in individuals with known hypersensitivity to macrogol or any of its excipients, in cases of complete intestinal obstruction, and in patients with severe renal impairment without medical supervision. It should also be avoided in those with acute abdominal conditions such as perforated bowel or inflammatory bowel disease flare‑ups unless directed by a physician.