Product image of Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Movicol, is an osmotic laxative presented as a powder for oral solution for oral use. It relieves constipation by softening stool and promoting bowel movements in adults and children, and includes electrolytes such as sodium hydrogen carbonate, potassium chloride and sodium chloride to help maintain fluid balance.

GNH India supplies Movicol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Healthcare B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Movicol is an osmotic laxative that acts on the gastrointestinal tract to treat various forms of constipation.
  • Constipation: softens stool and facilitates regular bowel movements.
  • Opioid‑induced constipation: counteracts reduced gut motility caused by opioid therapy.
  • Chronic idiopathic constipation: helps maintain long‑term bowel regularity in patients with persistent constipation.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is minimally absorbed in the gut. It creates an osmotic gradient that retains water within the intestinal lumen, increasing stool water content, softening the feces and stimulating peristalsis. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help preserve electrolyte balance during the laxative effect.

Side Effects

Movicol may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: mild upset stomach.
  • Abdominal cramps: intermittent stomach pain.
  • Diarrhoea: loose stools occurring more frequently.
  • Thirst: increased sensation of needing fluids.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels.
  • Severe dehydration: excessive loss of body fluids.
  • Allergic reaction: rash, itching, swelling, or angioedema.
  • Severe abdominal pain: intense, persistent pain.
  • Rectal bleeding: blood in stool indicating possible mucosal injury.

Precautions & Warnings

  • Before using Movicol, consider the following safety measures.
  • Renal impairment: monitor fluid and electrolyte status closely.
  • Heart failure: use with caution due to additional sodium load.
  • Electrolyte disorders: avoid in patients with hypernatremia or hyperkalemia.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Drug interactions: review concomitant medications that affect electrolyte balance.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Movicol can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Loop diuretics: increased risk of electrolyte disturbances.
  • Lithium: potential elevation of lithium serum concentrations.
  • ACE inhibitors or ARBs: may exacerbate hyperkalemia.

Moderate Interactions (Monitor Closely)

  • Other osmotic laxatives: additive effect leading to diarrhoea.
  • Sodium‑containing antacids: may increase overall sodium intake.
  • Corticosteroids: can influence fluid and electrolyte balance.

Frequently Asked Questions

Movicol is used to treat constipation, including chronic idiopathic constipation and constipation caused by opioid therapy. It works by softening the stool and promoting regular bowel movements, helping patients achieve relief from infrequent or difficult defecation.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that remains largely unabsorbed in the gastrointestinal tract. It creates an osmotic gradient that draws water into the intestinal lumen, increasing stool water content, softening the feces and stimulating peristalsis to facilitate evacuation.

The dose of Movicol is individualized by the prescribing healthcare professional based on the patient’s age, severity of constipation and response to therapy. The prescriber determines the appropriate amount of powder to dissolve in water for each administration.

Safety of Movicol in pregnancy or while breastfeeding has not been definitively established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using the product.

To order Movicol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Movicol (macrogol 3350) is an osmotic laxative that directly retains water in the bowel, whereas lactulose is a synthetic disaccharide that is fermented by colonic bacteria to produce osmotic acids. Movicol generally produces a faster onset of softer stools with fewer gas‑related side effects, while lactulose may be preferred for hepatic encephalopathy management.

Movicol should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the powder from moisture and direct sunlight. Keep the container tightly closed when not in use to maintain product stability.

Movicol is supplied as a powder that is dissolved in a measured amount of water, usually 125 mL, to create an oral solution. The solution is taken by mouth as directed by the prescriber, typically once daily, with or without food.

Serious risks include severe electrolyte imbalance (especially sodium or potassium disturbances), significant dehydration, and rare allergic reactions such as rash, swelling or angioedema. Patients should seek immediate medical attention if they experience symptoms like extreme weakness, irregular heartbeat, severe abdominal pain or signs of an allergic response.

Movicol should be avoided in individuals with known hypersensitivity to macrogol or any of its components, in patients with severe renal impairment, uncontrolled heart failure, or existing electrolyte disorders such as hypernatremia or hyperkalemia, unless advised otherwise by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.