Product image of Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Movicol, is a osmotic laxative presented as an oral solution for oral use. It treats constipation, occasional constipation and fecal impaction in adults and children.
GNH India supplies Movicol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Healthcare B.V.

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Indications & Clinical Uses

Movicol, an osmotic laxative, works within the gastrointestinal tract to relieve constipation.

  • Constipation: softens stool and facilitates regular bowel movements.
  • Occasional constipation: provides temporary relief of infrequent bowel irregularities.
  • Fecal impaction: helps to loosen impacted stool for easier evacuation.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is minimally absorbed. It remains in the intestinal lumen and retains water osmotically, increasing stool water content, softening the feces and promoting peristalsis, while the accompanying electrolytes help maintain fluid balance.

Side Effects

Common Side Effects

  • Abdominal bloating: mild distension of the abdomen.
  • Nausea: feeling of sickness.
  • Diarrhoea: loose stools.
  • Flatulence: excess gas.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels that may require medical attention.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing indicating possible hypersensitivity.

Precautions & Warnings

Precautions should be observed before and during use of Movicol.

  • Renal impairment: assess kidney function prior to initiation.
  • Electrolyte disorders: monitor sodium and potassium levels during therapy.
  • Dehydration: ensure adequate fluid intake to avoid excessive fluid loss.
  • Pediatric use: dose adjustment and medical supervision are required for children.
  • Pregnancy and breastfeeding: use only if clearly needed after professional evaluation.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Movicol may interact with other medicines.

Major Interactions (Avoid)

  • Lithium: increased lithium levels may cause toxicity.
  • Digoxin: altered serum electrolytes can affect digoxin activity.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance electrolyte loss.
  • Antacids containing magnesium or aluminum: can affect osmotic balance.
  • Other laxatives: concurrent use may cause excessive fluid loss.

Frequently Asked Questions

Movicol is an osmotic laxative indicated for the relief of constipation, occasional constipation and the management of fecal impaction. It works by increasing the water content of stool, making bowel movements easier and more regular.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that is not absorbed from the gut. It retains water in the intestinal lumen by osmosis, softening the stool and stimulating peristalsis, while the added electrolytes help maintain fluid balance.

The dose of Movicol is individualized. A qualified prescriber determines the appropriate amount based on the patient’s age, severity of constipation and clinical condition. Patients should follow the specific instructions provided by their healthcare professional.

Safety data for Movicol during pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk, and only under the guidance of a qualified healthcare provider.

To order Movicol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Movicol provides a gentler, osmotic mechanism that softens stool without stimulating intestinal muscles. It is often preferred over lactulose for rapid relief, and it can be used alongside other treatments when a step‑wise approach to constipation is required.

Movicol should be stored at ambient temperature, below 25 °C, in its original container. Protect the solution from moisture and direct heat. Keep the bottle tightly closed when not in use to maintain product stability.

Movicol is supplied as an oral solution. The prescribed amount is typically mixed with a measured volume of water, stirred until fully dissolved, and then consumed. It should be taken as directed by a healthcare professional, usually with or without food.

Serious risks include severe electrolyte imbalance, which can cause cardiac or neurological symptoms, and allergic reactions such as rash, swelling or breathing difficulty. Patients experiencing these signs should seek immediate medical attention.

Movicol should be avoided in individuals with known hypersensitivity to any of its components, in patients with severe renal impairment without medical supervision, and in those with obstructive gastrointestinal conditions where increased stool water could worsen the blockage.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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