Product image of Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Movicol, is an osmotic laxative presented as a powder for oral solution for oral use. It treats constipation, including chronic constipation and faecal impaction, in adults and children when directed by a healthcare professional. The formulation also contains sodium hydrogen carbonate, potassium chloride and sodium chloride to help maintain electrolyte balance.

GNH India supplies Movicol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Healthcare B.V.

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Indications & Clinical Uses

Movicol, an osmotic laxative, is used to manage conditions that involve reduced bowel motility.

  • Constipation: softens stool and promotes regular bowel movements.
  • Chronic constipation: provides sustained relief for long‑term bowel regularity.
  • Faecal impaction: facilitates evacuation of hardened stool in acute blockage.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polymer that is minimally absorbed in the gastrointestinal tract. It retains water in the intestinal lumen by osmosis, increasing stool water content, softening the feces and stimulating peristalsis. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help maintain electrolyte balance during the laxation process.

Side Effects

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased gas production.
  • Nausea: mild discomfort or urge to vomit.
  • Diarrhoea: loose, watery stools.
  • Headache: mild to moderate head pain.
  • Abdominal discomfort: cramping or mild pain.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: intense, persistent pain.
  • Dehydration: excessive fluid loss leading to dizziness.
  • Renal impairment: worsening kidney function in susceptible individuals.

Precautions & Warnings

Before using Movicol, consider the following precautions:

  • Assess renal function: avoid or adjust use in patients with severe renal impairment.
  • Monitor electrolytes: watch for hypernatremia or hypokalemia due to electrolyte content.
  • Contraindication in obstruction: do not use if intestinal blockage is present.
  • Pregnancy caution: limited data; use only if clearly needed.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Movicol may interact with other medicines as follows:

Major Interactions (Avoid)

  • Other osmotic laxatives: increased risk of severe electrolyte disturbances.
  • Loop diuretics: may exacerbate electrolyte loss.
  • Lithium: altered renal clearance can raise lithium levels.

Moderate Interactions (Monitor Closely)

  • Antacids containing magnesium or aluminium: may affect laxative efficacy.
  • Warfarin: possible alteration of INR values.
  • Quinolone antibiotics: may reduce the effectiveness of the laxative.

Frequently Asked Questions

Movicol is an osmotic laxative indicated for the relief of constipation, chronic constipation and faecal impaction. It works by increasing water in the intestinal lumen to soften stool and promote bowel movements.

Macrogol 3350 is a large polymer that remains in the gut and draws water into the intestinal lumen by osmosis. This added water softens the stool and stimulates peristalsis, facilitating easier passage of feces.

The dose of Movicol is individualized by a prescriber based on the patient’s age, condition severity and response. Patients should follow the specific instructions provided by their healthcare professional.

Safety data for Movicol in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk, and under the guidance of a qualified healthcare provider.

To order Movicol, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Movicol works osmotically and generally causes fewer cramping side effects. Unlike bulk‑forming agents, it does not rely on dietary fiber and provides rapid softening of stool, making it suitable for acute and chronic constipation.

Store Movicol at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed and protect it from moisture to maintain product stability.

Movicol is supplied as a powder that is dissolved in water to make an oral solution. The patient should stir the mixture until fully dissolved and drink the solution as directed by the prescriber.

Serious risks include severe electrolyte imbalance, allergic reactions such as rash or breathing difficulty, and dehydration. Patients experiencing these symptoms should seek medical attention promptly.

Movicol should be avoided in individuals with known intestinal obstruction, severe renal impairment, or hypersensitivity to any of its components. It should also be used with caution in patients on medications that affect electrolyte balance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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