Product image of Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Movicol, is a osmotic laxative presented as a oral solution for oral use. It treats constipation and faecal impaction in adults and children.
GNH India supplies Movicol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Limited

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Indications & Clinical Uses

  • Movicol is an osmotic laxative used to manage conditions affecting bowel motility and stool consistency.
  • Constipation: softens stool and facilitates regular bowel movements.
  • Faecal impaction: helps break down hardened stool masses for easier evacuation.
  • Chronic idiopathic constipation: provides long‑term relief by maintaining stool hydration.

How It Works

  • Macrogol 3350 creates an osmotic gradient in the intestinal lumen, drawing water into the bowel. The increased water content softens fecal mass, expands the stool volume, and stimulates peristalsis, thereby promoting regular bowel movements without stimulating intestinal secretions directly.

Side Effects

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Nausea: mild to moderate sensation of wanting to vomit.
  • Flatulence: increased intestinal gas.
  • Diarrhoea: loose, watery stools.
  • Abdominal pain: cramping or discomfort.
  • Thirst: increased desire for fluids.

Serious or Rare Side Effects

  • Electrolyte imbalance: abnormal levels of sodium, potassium, or chloride.
  • Severe dehydration: marked loss of body fluids.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: persistent or worsening pain requiring medical attention.

Precautions & Warnings

Before using Movicol, consider the following precautions:

  • Renal function assessment: evaluate kidney health to avoid fluid overload.
  • Electrolyte monitoring: check serum electrolytes, especially in long‑term use.
  • Bowel obstruction: avoid if there is known mechanical blockage.
  • Elderly patients: start with lower doses and monitor tolerance.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Movicol may interact with other medications as follows:

Major Interactions (Avoid)

  • Loop diuretics: increased risk of electrolyte disturbances.
  • Mineralocorticoid therapy: may exacerbate sodium and water retention.
  • Other osmotic laxatives: additive effect leading to severe dehydration.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminium or magnesium: may alter absorption.
  • NSAIDs: potential for reduced renal clearance when combined.
  • ACE inhibitors: monitor blood pressure and renal function.

Frequently Asked Questions

Movicol is an oral osmotic laxative indicated for the relief of constipation and the treatment of faecal impaction. It works by increasing water content in the intestine, softening stool and promoting regular bowel movements in adults and children.

Macrogol 3350 acts as an osmotic agent that retains water within the intestinal lumen. By drawing water into the bowel, it softens the stool, expands its volume, and stimulates peristalsis, which together facilitate easier and more frequent evacuation.

The dose of Movicol is individualized by the prescribing healthcare professional based on the patient’s age, severity of constipation, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for Movicol in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks before prescribing it to pregnant or nursing individuals. Consultation with a physician is essential.

To order Movicol, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Movicol provides a gentler, water‑based mechanism that softens stool without causing cramping. It is often preferred for chronic constipation because it has a lower risk of dependence and a more favorable tolerability profile.

Store Movicol at room temperature, preferably below 25 °C. Keep the solution in its original container, protect it from moisture and direct sunlight, and ensure the cap is tightly closed to maintain product stability.

Movicol is taken orally as a liquid solution. The prescribed amount is usually mixed with a measured volume of water, shaken gently, and consumed immediately. Patients should drink the full mixture and may follow it with additional water if advised.

Serious risks include electrolyte imbalance, severe dehydration, and rare allergic reactions. Patients should seek medical attention if they experience symptoms such as rapid heartbeat, muscle weakness, severe abdominal pain, swelling, or difficulty breathing.

Movicol should be avoided in individuals with known mechanical bowel obstruction, severe renal impairment, or hypersensitivity to any of its components. It is also contraindicated in patients who are on certain electrolyte‑altering medications without appropriate monitoring.

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GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

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