Product image of Movicol Unidose (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol Unidose

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol Unidose (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350, the active ingredients in Movicol Unidose, is an osmotic laxative presented as an oral powder for solution for oral use. It relieves constipation by increasing stool water content in adults and children.

GNH India supplies Movicol Unidose as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Nv/Sa

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Indications & Clinical Uses

Movicol Unidose, an osmotic laxative, is used to manage conditions involving reduced bowel motility.

  • Chronic constipation: helps soften stool and promote regular bowel movements.
  • Faecal impaction: facilitates evacuation of hardened stool.
  • Bowel preparation for colonoscopy: provides effective cleansing of the colon.

How It Works

  • Macrogol 3350 creates an osmotic gradient that retains water in the intestinal lumen, increasing stool volume and softness. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) maintain electrolyte balance while the solution promotes intestinal transit without stimulating secretory pathways.

Side Effects

Common Side Effects

  • Abdominal bloating: mild distension of the abdomen.
  • Nausea: feeling of sickness or urge to vomit.
  • Flatulence: increased intestinal gas.
  • Diarrhoea: loose, watery stools.
  • Stomach cramps: intermittent abdominal pain.
  • Thirst: increased desire for fluids.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: abnormal sodium or potassium levels.
  • Dehydration: excessive loss of body water.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Severe abdominal pain: persistent, intense pain.
  • Blood in stool: presence of visible blood.
  • Renal dysfunction: impaired kidney function.

Precautions & Warnings

Before using Movicol Unidose, consider the following safety measures.

  • Assess renal function: evaluate kidney status before initiating therapy.
  • Monitor electrolytes: watch for sodium and potassium changes during prolonged use.
  • Use caution in dehydration: ensure adequate fluid intake while on treatment.
  • Avoid in intestinal obstruction: contraindicated in mechanical blockage of the bowel.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Movicol Unidose may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Lithium: increased risk of toxicity due to altered absorption.
  • Diuretics: may exacerbate electrolyte disturbances.
  • Digoxin: risk of altered potassium levels affecting cardiac activity.

Moderate Interactions (Monitor Closely)

  • Antacids: may affect osmotic balance and reduce efficacy.
  • Oral antibiotics: possible reduced absorption of the antibiotic.
  • Warfarin: monitor INR as fluid shifts may influence anticoagulant levels.

Frequently Asked Questions

Movicol Unidose is an oral osmotic laxative used to treat chronic constipation, relieve faecal impaction, and provide bowel cleansing before procedures such as colonoscopy. It works by increasing the water content of stool, making evacuation easier.

Macrogol 3350 is a high‑molecular‑weight polyethylene glycol that creates an osmotic gradient in the intestine, drawing water into the lumen. This softens stool, increases its volume, and promotes peristalsis without stimulating secretory pathways.

The dose of Movicol Unidose is determined by the prescribing healthcare professional based on the patient’s age, condition, and response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Movicol Unidose.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with stimulant laxatives, Movicol Unidose provides gentle, water‑based stool softening without causing cramping. Its electrolyte‑balanced formulation reduces the risk of significant electrolyte loss, making it suitable for longer‑term use in many patients.

Store Movicol Unidose at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Movicol Unidose is supplied as a powder that is dissolved in water or another clear fluid as instructed by the prescriber. The solution is then taken orally, usually once daily, with or without food, according to the healthcare professional’s guidance.

Serious risks include severe electrolyte imbalance, dehydration, allergic reactions, and rare cases of renal dysfunction. Patients should seek immediate medical attention if they experience symptoms such as rapid heartbeat, severe abdominal pain, swelling, or blood in the stool.

Movicol Unidose should be avoided in individuals with known mechanical intestinal obstruction, severe renal impairment, or hypersensitivity to any of its components. It is also contraindicated in patients who have experienced severe electrolyte disturbances without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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