Product image of Movicol Unidose (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicol Unidose

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicol Unidose (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350 with electrolytes, the active ingredient in Movicol Unidose, is an osmotic laxative presented as a powder for oral solution for oral use. It treats constipation, including occasional cases, and is used for bowel preparation before diagnostic procedures as directed by a healthcare professional.

GNH India supplies Movicol Unidose as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Nv/Sa

1
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Indications & Clinical Uses

Movicol Unidose is an osmotic laxative that works within the gastrointestinal tract to relieve constipation and prepare the bowel for procedures.

  • Constipation: softens stool and promotes regular bowel movements.
  • Occasional constipation: provides rapid relief of infrequent constipation episodes.
  • Bowel preparation for diagnostic procedures: clears the intestinal lumen to improve visibility during colonoscopy or imaging studies.

How It Works

  • Macrogol 3350 creates an osmotic gradient in the intestinal lumen, drawing water into the bowel. The retained water softens stool, increases stool volume, and stimulates peristalsis, facilitating easier passage of feces. The accompanying electrolytes help maintain fluid balance while enhancing the laxative effect.

Side Effects

Movicol Unidose may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal bloating: feeling of fullness or swelling in the abdomen.
  • Flatulence: increased intestinal gas.
  • Nausea: mild sensation of wanting to vomit.
  • Mild abdominal pain or cramps.
  • Diarrhoea: loose, watery stools.
  • Thirst: increased desire to drink fluids.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body fluids.
  • Electrolyte imbalance: abnormal levels of sodium, potassium, or chloride.
  • Allergic reaction: rash, itching, swelling, or angioedema.
  • Severe abdominal pain: intense or persistent pain.
  • Rectal bleeding: presence of blood in stool.

Precautions & Warnings

Before using Movicol Unidose, consider the following safety measures.

  • Renal function assessment: evaluate kidney health to avoid fluid overload.
  • Electrolyte monitoring: check serum electrolytes, especially in patients at risk.
  • Use with caution in the elderly: increased susceptibility to dehydration.
  • Avoid in bowel obstruction: contraindicated when intestinal blockage is present.
  • Adjust dose in hepatic impairment: consider liver function status.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Movicol Unidose can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Other osmotic laxatives: risk of excessive fluid loss and electrolyte disturbances.
  • Loop diuretics: may amplify electrolyte depletion.
  • Lithium: altered lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may reduce laxative efficacy.
  • NSAIDs: potential impact on renal function.
  • ACE inhibitors: monitor for changes in blood pressure and electrolytes.

Frequently Asked Questions

Movicol Unidose is indicated for the relief of constipation, including occasional episodes, and for bowel preparation before diagnostic procedures such as colonoscopy. It works by softening stool and increasing bowel movements, helping to clear the intestinal tract.

Macrogol 3350 acts as an osmotic agent that retains water in the intestinal lumen. The added water softens the stool, expands its volume, and stimulates peristalsis, which together facilitate easier and more regular bowel movements.

The dose of Movicol Unidose is individualized and set by the prescribing healthcare professional based on the patient’s age, condition, and response to therapy. Patients should follow the specific instructions provided by their prescriber.

Safety data for Movicol Unidose in pregnancy and lactation are limited. The prescriber should evaluate the potential benefits against any possible risks before recommending use in pregnant or breastfeeding individuals.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Movicol Unidose works osmotically, offering a gentler mechanism that retains water in the bowel rather than stimulating muscle contractions. This often results in fewer cramping side effects, making it suitable for patients needing a milder, electrolyte‑balanced option.

Store Movicol Unidose at ambient temperature, below 25 °C, in its original packaging. Protect the powder from moisture and direct sunlight to maintain its stability and efficacy.

Movicol Unidose is supplied as a powder that is dissolved in water to create an oral solution. The prepared solution is taken by mouth, usually once daily or as directed by the prescriber, with a full glass of water.

Serious risks include severe dehydration, electrolyte imbalance (particularly low sodium or potassium), and rare allergic reactions such as rash or angioedema. Patients should seek medical attention if they experience signs of these conditions.

Movicol Unidose should be avoided in individuals with known bowel obstruction, severe renal impairment, or hypersensitivity to any of its components. It should also be used with caution in patients with electrolyte disorders or those taking interacting medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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