Product image of Movicolon Naturel (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Movicolon Naturel

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Movicolon Naturel (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Sodium Hydrogen Carbonate, the active ingredient in Movicolon Naturel, is an osmotic laxative presented as a powder for oral use. It helps relieve constipation by increasing water content in the intestine and is also used for bowel preparation.
GNH India supplies Movicolon Naturel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine Healthcare B.V.

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Indications & Clinical Uses

  • Movicolon Naturel is an oral osmotic laxative that works on the gastrointestinal tract to soften stool and facilitate evacuation.
  • Constipation: provides an osmotic effect that increases stool water content, easing passage.
  • Bowel preparation for colonoscopy: cleanses the colon by promoting thorough evacuation.
  • Irritable bowel syndrome with constipation: alleviates symptoms by regularising bowel movements.

How It Works

  • Macrogol 3350 is a high‑molecular‑weight polymer that remains in the intestinal lumen and retains water, creating an osmotic gradient. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) maintain electrolyte balance while the increased fluid softens stool and stimulates peristalsis, resulting in easier bowel movements.

Side Effects

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Nausea
  • Mild abdominal cramps
  • Diarrhoea
  • Increased thirst

Serious or Rare Side Effects

  • Severe electrolyte imbalance (e.g., hypernatremia, hypokalemia)
  • Dehydration
  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Severe abdominal pain
  • Rectal bleeding

Precautions & Warnings

Precautions should be observed when using Movicolon Naturel to minimise risks.

  • Assess renal function: adjust use in patients with renal impairment.
  • Monitor electrolytes: especially in individuals on diuretics or with heart failure.
  • Use with caution in the elderly: higher risk of dehydration.
  • Avoid in intestinal obstruction or perforation: may worsen the condition.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Movicolon Naturel may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Loop diuretics: may cause significant electrolyte disturbances.
  • Potassium‑sparing diuretics: risk of hyperkalaemia.
  • ACE inhibitors or ARBs: monitor potassium levels closely.

Moderate Interactions (Monitor Closely)

  • Other laxatives: risk of excessive fluid loss.
  • Oral rehydration solutions: may require electrolyte adjustment.

Frequently Asked Questions

Movicolon Naturel is an oral osmotic laxative indicated for the relief of occasional constipation and for bowel cleansing before diagnostic procedures such as colonoscopy. By increasing the water content within the intestinal lumen, it softens stool and promotes easier passage, providing a gentle yet effective option for patients needing regular bowel regulation.

Macrogol 3350 is a high‑molecular‑weight polymer that is not absorbed from the gut. It creates an osmotic gradient that draws water into the intestinal lumen, while the accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help maintain normal electrolyte balance. The resulting increase in fluid softens stool and stimulates peristalsis, facilitating bowel movements.

The specific dose of Movicolon Naturel is determined by the prescribing healthcare professional based on the patient’s condition, age, and response. Dosage may differ for constipation relief versus bowel preparation, and the prescriber will provide written instructions on the amount of powder to mix with water and the timing of administration.

Safety in pregnancy and lactation has not been fully established. The product should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their doctor.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with stimulant laxatives, Movicolon Naturel (macrogol 3350‑based) acts osmotically, softening stool without directly stimulating intestinal muscle, which often results in fewer cramping side effects. Unlike saline laxatives, it includes electrolytes to reduce the risk of significant electrolyte shifts. It is generally preferred for chronic constipation and bowel preparation when a gentle, well‑tolerated option is desired.

Movicolon Naturel should be stored at ambient temperature, below 25 °C, in its original packaging. The container must be kept tightly closed to protect the powder from moisture and humidity, which could affect product stability. Keep the product out of direct sunlight and away from sources of heat.

The powder is reconstituted in a measured amount of water as directed by the prescriber, typically 125 mL to 250 mL, and the solution is consumed orally. It may be taken with or without food, but patients should follow the specific timing instructions (e.g., on an empty stomach for bowel preparation). The mixture should be shaken gently to ensure complete dissolution before drinking.

Although uncommon, serious adverse events can include severe electrolyte disturbances such as hypernatremia or hypokalemia, marked dehydration, and allergic reactions presenting as rash, swelling, or difficulty breathing. Patients experiencing intense abdominal pain, persistent diarrhoea, or signs of electrolyte imbalance should seek immediate medical attention. Monitoring is especially important in individuals with renal, cardiac, or hepatic disease.

Movicolon Naturel is contraindicated in patients with known or suspected intestinal obstruction, perforation, or an active flare‑up of inflammatory bowel disease, as well as in those with severe renal impairment where electrolyte handling is compromised. Individuals with hypersensitivity to any of the listed ingredients should avoid the product. Use should be carefully evaluated by a healthcare professional in patients with heart failure or on medications that affect fluid and electrolyte balance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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