Product image of Movin (Cinnarizine, Dimenhydrinate) supplied by GNH India

Movin

Active Ingredient:
Cinnarizine, Dimenhydrinate
Origin:
EU

Movin (Cinnarizine, Dimenhydrinate)

Cinnarizine and Dimenhydrinate, the active ingredients in Movin, are an antihistamine and calcium‑channel blocker presented as an oral tablet for oral use. They are employed to alleviate motion‑induced vertigo, nausea and vomiting in adults, adolescents and children over six years of age.

GNH India supplies Movin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑controlled batches for global distribution and meeting regulatory requirements of the European Union market. The product is manufactured under GMP standards and shipped in tamper‑evident packaging.

Manufacturer / TM Owner

Tetrafarma- Produtos Farmacêuticos, Lda.

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Indications & Clinical Uses

Movin, containing cinnarizine and dimenhydrinate, is indicated for conditions affecting the vestibular system and gastrointestinal tract related to motion.

  • Motion sickness: Reduces dizziness, nausea and vomiting associated with travel by land, sea or air.
  • Vertigo: Alleviates spinning sensations and balance disturbances caused by inner‑ear disorders.
  • Nausea and vomiting: Controls acute episodes of nausea and vomiting not related to motion, such as postoperative or medication‑induced cases.

How It Works

  • Cinnarizine blocks voltage‑dependent calcium channels and antagonizes H1 histamine receptors, decreasing vestibular excitability, while dimenhydrinate acts as an H1 receptor antagonist with anticholinergic properties, suppressing vestibular stimulation and the central vomiting centre, together reducing symptoms of motion‑related vertigo and nausea.

Side Effects

Adverse reactions to Movin are generally mild but can vary in frequency and severity.

Common Side Effects

  • Drowsiness
  • Dry mouth
  • Headache

Serious or Rare Side Effects

  • Extrapyramidal symptoms (e.g., tremor, rigidity)
  • Severe allergic reaction (anaphylaxis)
  • Cardiac arrhythmia

Precautions & Warnings

When using Movin, consider the following safety measures.

  • Avoid operating machinery: Drowsiness may impair alertness.
  • Use with caution in the elderly: Increased sensitivity to sedative effects.
  • Do not combine with other antihistamines or sedatives without medical advice.
  • Monitor for signs of extrapyramidal reactions, especially with prolonged use.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Movin may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Concomitant use with central nervous system depressants (e.g., benzodiazepines, opioids).
  • Combination with other antihistamines.
  • Use with monoamine oxidase inhibitors (MAOIs).

Moderate Interactions (Monitor Closely)

  • Alcohol consumption.
  • Anticholinergic drugs (e.g., atropine, scopolamine).
  • CYP2D6 substrates that may have altered metabolism.
  • Loop diuretics (potential additive hypotensive effect).
  • Other antiemetics with overlapping mechanisms.

Frequently Asked Questions

Movin is prescribed to prevent and treat motion‑induced vertigo, nausea and vomiting, as well as to manage episodes of vertigo unrelated to travel and other forms of acute nausea. It is commonly used for motion sickness, vestibular disorders and occasional emesis.

Cinnarizine blocks calcium channels and antagonizes H1 histamine receptors, reducing inner‑ear excitability. Dimenhydrinate also blocks H1 receptors and adds anticholinergic activity, dampening vestibular signals to the brain. Together they provide a synergistic effect that lessens dizziness and the urge to vomit.

The specific dose of Movin is determined by the prescribing clinician based on the patient’s age, weight, severity of symptoms and medical history. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety data for cinnarizine and dimenhydrinate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified health professional.

To request Movin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient antihistamines such as meclizine, Movin combines two agents that target both histamine receptors and calcium channels, offering broader symptom control. It may provide faster relief for severe vertigo, but individual response varies and clinicians choose therapy based on patient profile.

Store Movin at room temperature, preferably below 25 °C. Keep the tablets in the original blister pack, protect them from moisture, heat and direct sunlight to maintain potency throughout the shelf life.

Movin is taken orally with a glass of water. It can be taken with or without food, but patients should follow the prescribing information regarding timing relative to travel or onset of symptoms.

Serious risks include extrapyramidal reactions such as tremor or rigidity, severe allergic responses (anaphylaxis), and cardiac arrhythmias. Patients should seek immediate medical attention if they experience muscle stiffness, difficulty breathing, rash, or irregular heartbeats.

Movin is contraindicated in individuals with known hypersensitivity to cinnarizine, dimenhydrinate or any component of the formulation. It should also be avoided in patients with severe Parkinsonian disease, uncontrolled epilepsy, or those taking interacting CNS depressants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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