Product image of Moviprep (Ascorbic Acid, Sodium Ascorbate, Potassium Chloride, Sodium Chloride, Sodium Sulfate Anhydrous, Macr) supplied by GNH India

Moviprep

Active Ingredient:
Ascorbic Acid, Sodium Ascorbate, Potassium Chloride, Sodium Chloride, Sodium Sulfate Anhydrous, Macr
Origin:
EU

Moviprep (Ascorbic Acid, Sodium Ascorbate, Potassium Chloride, Sodium Chloride, Sodium Sulfate Anhydrous, Macr)

Polyethylene glycol 3350 with electrolytes and ascorbic acid, the active ingredient in Moviprep, is an osmotic laxative presented as a powder for oral solution for oral use. It is used to cleanse the bowel before colonoscopy, sigmoidoscopy, and radiological examinations of the colon.

GNH India supplies Moviprep as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norgine B.V.

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Indications & Clinical Uses

Moviprep, an osmotic laxative used for bowel preparation, is indicated for:

  • Bowel cleansing prior to colonoscopy: achieves thorough colon cleansing to allow clear visualization during the procedure.
  • Bowel cleansing prior to sigmoidoscopy: provides effective evacuation of stool for optimal sigmoidoscopic examination.
  • Bowel cleansing prior to radiological examinations of the colon: ensures adequate preparation for contrast imaging of the colon.

How It Works

  • Moviprep contains polyethylene glycol 3350, a large, non‑absorbable polymer that creates an osmotic gradient, drawing water into the intestinal lumen. The accompanying electrolytes (sodium, potassium, chloride, sulfate) maintain fluid and electrolyte balance, while ascorbic acid enhances the osmotic effect, together promoting rapid and complete bowel evacuation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate feeling of sickness.
  • Abdominal discomfort: cramping or pain in the abdomen.
  • Bloating: sensation of fullness or gas.
  • Vomiting: occasional expulsion of stomach contents.
  • Headache: transient mild headache.
  • Thirst: increased desire for fluids.

Serious or Rare Side Effects

  • Severe dehydration: marked loss of body fluids requiring medical attention.
  • Electrolyte imbalance: abnormal sodium or potassium levels that may affect heart rhythm.
  • Acute renal impairment: sudden decline in kidney function.
  • Severe abdominal pain: intense pain that does not resolve.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Hypotension: unusually low blood pressure.

Precautions & Warnings

Before using Moviprep, consider the following precautions:

  • Assess renal function: evaluate kidney function prior to initiation.
  • Review electrolyte status: check serum sodium, potassium and other electrolytes.
  • Ensure adequate hydration: advise patients to drink sufficient fluids during preparation.
  • Avoid in intestinal obstruction: contraindicated in known or suspected obstruction.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Moviprep may interact with other medicines as follows:

Major Interactions (Avoid)

  • Other osmotic laxatives: risk of excessive fluid and electrolyte loss.
  • Antidiarrheal agents (e.g., loperamide): may reduce efficacy of bowel cleansing.
  • Diuretics or ACE inhibitors: can exacerbate electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • Lithium therapy: fluid shifts may alter lithium serum levels.
  • Oral rehydration solutions: may affect overall electrolyte composition.
  • Antacids containing magnesium or aluminum: could interfere with absorption of electrolytes.

Frequently Asked Questions

Moviprep is a prescription‑only bowel‑cleansing agent indicated for preparation of the colon before colonoscopy, sigmoidoscopy, or radiological examinations of the colon. It works by producing an osmotic effect that promotes evacuation of intestinal contents, providing a clear view for diagnostic or therapeutic procedures.

The polyethylene glycol 3350 component is a large, non‑absorbable polymer that retains water in the intestinal lumen by osmosis. The added electrolytes (sodium, potassium, chloride, sulfate) maintain fluid balance, while ascorbic acid enhances the osmotic gradient, together facilitating rapid bowel evacuation.

The prescribed dose of Moviprep is individualized by the treating physician based on the patient’s age, weight, renal function, and the specific endoscopic procedure. The healthcare professional calculates the total volume of powder to be reconstituted and the timing of ingestion according to the product’s label instructions.

The safety of Moviprep in pregnancy or lactation has not been definitively established. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after evaluating the clinical situation.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with sodium‑picosulfate‑based or magnesium‑oxide preparations, Moviprep provides a balanced electrolyte solution and a rapid, high‑volume osmotic effect, which can result in more consistent colon cleansing. However, the larger fluid volume may be less convenient for some patients, and individual tolerance varies.

Store Moviprep at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the powder from moisture and direct sunlight. Do not refrigerate or freeze the product, as temperature extremes can affect its stability and efficacy.

Moviprep is supplied as a powder that must be dissolved in a specified volume of water to create an oral solution. The patient drinks the solution in divided doses as directed by the prescribing physician, usually the evening before and the morning of the procedure, while maintaining adequate fluid intake.

The most serious adverse events include severe dehydration, electrolyte disturbances (such as hyponatremia or hypokalemia), and rare cases of acute renal impairment. Patients should be monitored for signs of excessive fluid loss, dizziness, muscle cramps, or abnormal heart rhythms, and seek medical attention promptly if they occur.

Moviprep is contraindicated in individuals with known or suspected intestinal obstruction, perforation, severe inflammatory bowel disease, or significant renal impairment. It should also be avoided in patients with uncontrolled electrolyte imbalances or hypersensitivity to any of its components. A healthcare professional must assess suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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