Product image of Moxifloxacin Al (Moxifloxacin) supplied by GNH India

Moxifloxacin Al

Active Ingredient:
Moxifloxacin
Origin:
EU

Moxifloxacin Al (Moxifloxacin)

Moxifloxacin, the active ingredient in Moxifloxacin Al, is a fluoroquinolone presented as an oral tablet for oral use. It treats bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, and skin and skin structure infections in adult patients.

GNH India supplies Moxifloxacin Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. It is delivered through reliable logistics and comprehensive documentation.

Manufacturer / TM Owner

Aliud Pharma Gmbh

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Indications & Clinical Uses

Moxifloxacin is a fluoroquinolone antibiotic indicated for several bacterial respiratory and skin infections.

  • Community‑acquired pneumonia: effective in eradicating susceptible Streptococcus pneumoniae and other typical pathogens.
  • Acute bacterial sinusitis: reduces bacterial load and alleviates sinus inflammation.
  • Acute bacterial exacerbation of chronic bronchitis: improves symptoms and shortens disease duration.
  • Skin and skin structure infections: treats infections caused by Staphylococcus aureus and other Gram‑positive organisms.

How It Works

  • Moxifloxacin exerts its antibacterial activity by binding to bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. This inhibition prevents the supercoiling and relaxation of DNA that are essential for replication and transcription, leading to bacterial cell death. The dual targeting of both enzymes enhances potency against a broad spectrum of Gram‑positive and Gram‑negative organisms.

Side Effects

Moxifloxacin may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Tendon rupture or tendinitis
  • QT interval prolongation
  • Severe allergic reaction (anaphylaxis)

Precautions & Warnings

Before prescribing Moxifloxacin, clinicians should consider several safety precautions.

  • Assess renal function: adjust use in patients with severe impairment.
  • Monitor for tendon pain: discontinue if signs of tendinopathy appear.
  • Evaluate cardiac history: avoid in patients with known QT prolongation.
  • Review concomitant medications: avoid combinations that increase QT risk.
  • Check for hypersensitivity: do not use in individuals with known allergy to fluoroquinolones.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Moxifloxacin can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce absorption of the drug.
  • NSAIDs (e.g., ibuprofen): increase risk of central nervous system stimulation.
  • Warfarin: may enhance anticoagulant effect and raise bleeding risk.

Moderate Interactions (Monitor Closely)

  • CYP1A2 inhibitors (e.g., ciprofloxacin): may increase moxifloxacin plasma levels.
  • CYP3A4 inducers (e.g., rifampin): may lower drug concentration and reduce effectiveness.
  • Oral contraceptives: may experience reduced hormonal efficacy.

Frequently Asked Questions

Moxifloxacin Al is an oral fluoroquinolone antibiotic prescribed for adult patients with community‑acquired pneumonia, acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and skin or skin‑structure infections caused by susceptible bacteria.

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA supercoiling and replication. By blocking these targets, the drug prevents bacterial DNA synthesis and leads to rapid bacterial cell death across a broad spectrum of Gram‑positive and Gram‑negative organisms.

The prescribed dose of Moxifloxacin Al is determined by the treating physician based on the specific infection, patient age, renal function and other clinical factors. Dosage regimens may differ between indications, and the prescriber will provide the appropriate instructions.

Safety data for moxifloxacin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To request Moxifloxacin Al, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Moxifloxacin offers a broader spectrum against Gram‑positive organisms and better activity against atypical respiratory pathogens compared with older fluoroquinolones such as ciprofloxacin. It also has a once‑daily dosing schedule, which can improve patient adherence, but shares class‑related safety considerations.

Moxifloxacin Al tablets should be stored at temperatures below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date printed on the label.

Moxifloxacin Al is taken orally as a tablet with a full glass of water. It may be taken with or without food, but patients should follow the prescriber’s instructions regarding timing relative to meals to ensure optimal absorption.

Serious adverse events include tendon rupture or tendinitis, QT interval prolongation that can lead to arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should seek immediate medical attention if they experience unexplained tendon pain, palpitations, or signs of a severe allergic reaction.

Moxifloxacin Al is contraindicated in individuals with a known hypersensitivity to moxifloxacin or other fluoroquinolones, a history of tendon disorders related to fluoroquinolone use, or a documented prolonged QT interval. Caution is also advised for patients with severe renal impairment or those taking medications that prolong the QT interval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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