Product image of Moxifloxacin Brown & Burk Uk (Moxifloxacin Hydrochloride) supplied by GNH India

Moxifloxacin Brown & Burk Uk

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Moxifloxacin Brown & Burk Uk (Moxifloxacin Hydrochloride)

Moxifloxacin, the active ingredient in Moxifloxacin Brown & Burk Uk, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It exhibits broad activity against Gram‑positive and Gram‑negative ocular pathogens, providing rapid bacterial eradication. It treats bacterial eye infections such as conjunctivitis and keratitis in patients requiring prescription therapy.

GNH India supplies Moxifloxacin Brown & Burk Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on reliable quality and regulatory compliance.

Manufacturer / TM Owner

Brown & Burk Uk Limited

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Indications & Clinical Uses

Moxifloxacin is a fluoroquinolone antibiotic used to treat bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces ocular inflammation and clears infection caused by susceptible bacteria, improving comfort and preventing spread.
  • Bacterial keratitis: eradicates pathogenic bacteria in the cornea, promoting healing and preserving visual acuity.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By binding to the quinolone‑resistance‑determining region of these enzymes, it prevents DNA strand separation, halting bacterial replication and transcription, leading to cell death. This dual‑target action provides potent bactericidal activity against a broad spectrum of ocular pathogens, including both Gram‑positive and Gram‑negative species commonly implicated in eye infections. The drug penetrates ocular tissues efficiently, achieving therapeutic concentrations in the cornea and conjunctiva.

Side Effects

Moxifloxacin eye drops may cause local ocular reactions and, rarely, systemic or severe ocular events.

Common Side Effects

  • Eye irritation or burning
  • Stinging sensation
  • Redness of the conjunctiva
  • Blurred vision
  • Tearing
  • Temporary foreign body sensation

Serious or Rare Side Effects

  • Allergic reaction with swelling or rash
  • Corneal ulceration or thinning
  • Severe eye pain
  • Sudden loss of vision
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Systemic hypersensitivity

Precautions & Warnings

When using Moxifloxacin ophthalmic solution, follow these safety considerations.

  • Prescription use only: administer under the direction of a qualified eye care professional.
  • Hypersensitivity: avoid if the patient has known allergy to fluoroquinolones or any component of the formulation.
  • Corneal health: monitor for signs of toxicity, especially in patients with pre‑existing corneal disease.
  • Contact lens wear: discontinue lenses during treatment and resume only after therapy completion.
  • Concurrent infections: do not use for viral or fungal eye infections, as it is ineffective and may worsen the condition.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Moxifloxacin ophthalmic solution can interact with certain ocular and systemic agents.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: additive toxicity risk, especially tendon or CNS effects.
  • Topical anesthetic eye drops: increased corneal toxicity when combined.
  • Corticosteroid eye drops: may mask infection signs and reduce antibiotic efficacy.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: possible reduced drug penetration.
  • Non‑steroidal anti‑inflammatory eye drops: may increase ocular irritation.
  • Ocular antihistamine drops: monitor for additive discomfort.

Frequently Asked Questions

Moxifloxacin Brown & Burk Uk is an ophthalmic solution indicated for the treatment of bacterial eye infections, specifically bacterial conjunctivitis and bacterial keratitis. It targets susceptible ocular pathogens to reduce inflammation, clear infection, and help preserve visual function.

Moxifloxacin belongs to the fluoroquinolone class and works by inhibiting bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription; their inhibition stops bacterial cell division, leading to rapid bactericidal activity against a broad range of eye‑infecting bacteria.

The dosage regimen for Moxifloxacin ophthalmic solution is determined by the prescribing eye‑care professional based on the severity of the infection, patient age, and response to therapy. The prescriber will specify the number of drops, frequency, and duration of treatment.

Safety data for ocular use of moxifloxacin during pregnancy or lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician in consultation with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Moxifloxacin offers a broad spectrum of activity against both Gram‑positive and Gram‑negative ocular pathogens and provides high ocular tissue penetration. Compared with older fluoroquinolones such as ciprofloxacin, it often requires less frequent dosing and may retain activity against some resistant strains, though choice of therapy should follow local susceptibility patterns and physician judgment.

The ophthalmic solution should be stored at room temperature, preferably below 25 °C, in its original container. Protect the product from direct light and moisture, and keep the cap tightly closed when not in use. Do not freeze the solution.

The medication is applied as an eye drop. The prescriber will instruct the patient on the number of drops per eye, the frequency (e.g., twice daily), and the total duration of therapy. Patients should wash their hands before instillation and avoid contaminating the dropper tip.

Serious adverse events, although rare, include severe allergic reactions, corneal ulceration or thinning, sudden loss of vision, and systemic hypersensitivity such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience intense eye pain, worsening redness, swelling, or any signs of an allergic reaction.

The product should not be used by individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any excipients in the formulation. It is also contraindicated for viral or fungal eye infections, as it lacks activity against these pathogens and may delay appropriate therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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