Product image of Moxifloxacin Krka (Moxifloxacin) supplied by GNH India

Moxifloxacin Krka

Active Ingredient:
Moxifloxacin
Origin:
EU

Moxifloxacin Krka (Moxifloxacin)

Moxifloxacin, the active ingredient in Moxifloxacin Krka, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults, including acute bacterial sinusitis, exacerbations of chronic bronchitis, community‑acquired pneumonia, and skin and soft‑tissue infections.

GNH India supplies Moxifloxacin Krka as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare providers worldwide, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Moxifloxacin is indicated for bacterial infections affecting the respiratory and skin systems.

  • Acute bacterial sinusitis: reduces bacterial load and alleviates sinus inflammation.
  • Acute bacterial exacerbation of chronic bronchitis: improves symptoms and shortens disease course.
  • Community‑acquired pneumonia: eradicates causative pathogens and supports recovery.
  • Skin and skin structure infections: treats susceptible Gram‑positive and Gram‑negative organisms.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against a broad spectrum of Gram‑positive and Gram‑negative organisms.

Side Effects

Moxifloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Abdominal pain: cramping or discomfort.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Tendon rupture: especially Achilles tendon, may occur without warning.
  • QT interval prolongation: can lead to cardiac arrhythmias.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Clostridioides difficile infection: severe colitis.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Photosensitivity: increased skin reaction to sunlight.

Precautions & Warnings

Before prescribing Moxifloxacin, clinicians should evaluate patient‑specific risk factors.

  • Renal impairment: assess kidney function and adjust if necessary.
  • History of tendon disorders: avoid use in patients with prior tendon injury.
  • Concomitant QT‑prolonging drugs: monitor cardiac rhythm closely.
  • Pregnancy and lactation: reserve for situations where benefits outweigh potential risks.
  • Age >65 years: increased susceptibility to central nervous system effects.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Moxifloxacin can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Other fluoroquinolones: additive toxicity risk.
  • QT‑prolonging agents (e.g., quinidine, macrolides): may cause serious arrhythmias.
  • Antacids containing aluminum or magnesium: reduce moxifloxacin absorption.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: heightened risk of CNS effects.
  • Theophylline: possible increase in serum theophylline levels.

Frequently Asked Questions

Moxifloxacin Krka is a prescription‑only fluoroquinolone antibiotic used to treat several serious bacterial infections in adults, including acute bacterial sinusitis, acute exacerbations of chronic bronchitis, community‑acquired pneumonia, and skin and skin‑structure infections caused by susceptible organisms.

Moxifloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents the resealing of DNA strands, leading to bacterial cell death and a bactericidal effect against a broad range of Gram‑positive and Gram‑negative bacteria.

The specific dose and treatment duration of Moxifloxacin Krka are determined by the prescribing clinician based on the infection type, severity, patient age, renal function, and other clinical factors. Patients should follow the prescriber’s instructions and not alter the regimen without medical advice.

Safety data for moxifloxacin in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and only under direct medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Moxifloxacin offers a broader spectrum against Gram‑positive organisms and better activity in respiratory infections compared with some older fluoroquinolones. It also has a once‑daily dosing schedule, but shares class‑related safety considerations such as tendon toxicity and QT prolongation, which must be weighed against alternative agents.

Moxifloxacin Krka tablets should be stored at room temperature, below 25 °C, in the original blister pack or container to protect from moisture and light. Keep out of reach of children and do not use if the packaging is damaged.

Moxifloxacin Krka is taken orally, usually with a full glass of water. It may be taken with or without food, but antacids containing aluminum or magnesium should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture (especially Achilles), QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and hepatic dysfunction. Patients should seek immediate medical attention if they experience sudden tendon pain, palpitations, severe rash, or persistent diarrhea.

Moxifloxacin Krka should be avoided in patients with a known hypersensitivity to fluoroquinolones, a history of tendon disorders related to fluoroquinolone use, those taking other QT‑prolonging drugs without monitoring, and individuals with uncontrolled epilepsy or severe hepatic impairment unless benefits clearly outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.