Product image of Moxifloxacin Stada (Moxifloxacin) supplied by GNH India

Moxifloxacin Stada

Active Ingredient:
Moxifloxacin
Origin:
EU

Moxifloxacin Stada (Moxifloxacin)

Moxifloxacin, the active ingredient in Moxifloxacin Stada, is a fluoroquinolone presented as an injection for intravenous use. It treats bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and complicated skin and skin structure infections in adult patients.

GNH India supplies Moxifloxacin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

Moxifloxacin is a fluoroquinolone antibiotic indicated for several serious bacterial infections.

  • Community‑acquired pneumonia: achieves clinical cure and microbiological eradication in adult patients.
  • Acute bacterial sinusitis: reduces symptoms and eliminates the causative pathogens.
  • Acute bacterial exacerbations of chronic bronchitis: improves lung function and shortens disease duration.
  • Complicated skin and skin structure infections: provides bacterial clearance and promotes wound healing.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and chromosome segregation. By blocking these targets, the drug prevents bacterial DNA synthesis, leading to bactericidal activity against a broad range of Gram‑positive and Gram‑negative organisms.

Side Effects

Moxifloxacin may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Diarrhea: self‑limiting loose stools.
  • Headache: transient cranial discomfort.
  • Rash: mild skin erythema or pruritus.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or rupture, especially in the Achilles.
  • QT interval prolongation: cardiac rhythm changes that may lead to arrhythmia.
  • Severe hypersensitivity reactions: anaphylaxis or Stevens‑Johnson syndrome.
  • Clostridioides difficile infection: severe colitis following disruption of gut flora.

Precautions & Warnings

When using Moxifloxacin, consider the following precautions.

  • Renal impairment: adjust therapy based on renal function and monitor.
  • History of tendon disorders: avoid use or discontinue at first sign of tendon pain.
  • Cardiac risk: assess QT prolongation risk before initiating.
  • Concomitant CNS active drugs: monitor for seizures or CNS stimulation.
  • Pregnancy and lactation: use only if benefits outweigh risks; limited data.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Moxifloxacin can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce absorption; separate dosing by at least 2 hours.
  • Non‑dihydropyridine calcium channel blockers (e.g., verapamil): increase risk of QT prolongation.
  • Warfarin: may enhance anticoagulant effect; monitor INR closely.
  • Theophylline: increased plasma levels; monitor for toxicity.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may increase risk of central nervous system stimulation.
  • Corticosteroids: higher incidence of tendon disorders.
  • Diuretics (especially thiazides): may potentiate electrolyte disturbances.

Frequently Asked Questions

Moxifloxacin Stada is an intravenous fluoroquinolone antibiotic indicated for the treatment of community‑acquired pneumonia, acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and complicated skin and skin structure infections in adult patients.

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This blockade prevents bacterial DNA synthesis, leading to rapid bactericidal activity against a broad spectrum of Gram‑positive and Gram‑negative organisms.

The dosage and duration of Moxifloxacin Stada are determined by the prescribing clinician based on the infection type, severity, patient weight, renal function, and local guidelines. No fixed regimen is provided here.

Safety data in pregnancy and lactation are limited. The drug should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Moxifloxacin offers a broader gram‑positive coverage and a higher potency against atypical pathogens compared with older agents such as ciprofloxacin or levofloxacin. It also has a once‑daily dosing option for many indications, but it shares class‑related safety considerations like QT prolongation and tendon toxicity.

Moxifloxacin Stada should be stored refrigerated between 2 °C and 8 °C, protected from light, and must not be frozen or shaken. Keep the vials in their original packaging until use to maintain stability.

The product is supplied as a sterile injection for intravenous use. It is typically diluted in an appropriate compatible solution and administered by a qualified healthcare professional over the prescribed infusion time, following aseptic technique.

Serious adverse events include tendon rupture (especially Achilles), QT interval prolongation leading to arrhythmias, severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome, and Clostridioides difficile‑associated colitis. Patients should be monitored closely for any of these signs.

Moxifloxacin Stada is contraindicated in individuals with known hypersensitivity to moxifloxacin or other fluoroquinolones, a history of tendon disorders related to fluoroquinolone use, and patients with a predisposition to QT prolongation or uncontrolled cardiac arrhythmias.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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