Product image of Moxifloxacin Teva (Moxifloxacin Hydrochloride) supplied by GNH India

Moxifloxacin Teva

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Moxifloxacin Teva (Moxifloxacin Hydrochloride)

Moxifloxacin, the active ingredient in Moxifloxacin Teva, is a fluoroquinolone antibiotic presented as an injection for intravenous use. It treats bacterial infections in adult patients.

GNH India supplies Moxifloxacin Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Teva Gyógyszergyár Zrt

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Indications & Clinical Uses

Moxifloxacin Teva is a fluoroquinolone antibiotic used to treat serious bacterial infections.

  • Community‑acquired bacterial pneumonia: achieves clinical cure and bacterial eradication.
  • Acute bacterial sinusitis: reduces symptoms and eliminates pathogenic bacteria.
  • Acute exacerbation of chronic bronchitis: improves respiratory function and clears infection.
  • Skin and soft‑tissue infections: promotes healing by eradicating susceptible organisms.
  • Intra‑abdominal infections: provides broad‑spectrum coverage for mixed bacterial flora.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of bacterial DNA, leading to halted bacterial cell division and ultimately bacterial cell death.

Side Effects

Moxifloxacin may cause a range of adverse reactions.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Injection site pain
  • Elevated liver enzymes

Serious or Rare Side Effects

  • Tendon rupture or tendonitis
  • QT interval prolongation leading to arrhythmia
  • Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome)
  • Clostridioides difficile‑associated colitis
  • Hepatic failure
  • Severe skin reactions such as toxic epidermal necrolysis

Precautions & Warnings

Use of Moxifloxacin requires careful clinical assessment.

  • Renal impairment: adjust therapy based on renal function.
  • History of tendon disorders: avoid use due to risk of tendon rupture.
  • Cardiac arrhythmias: monitor QT interval during treatment.
  • Concurrent use with other QT‑prolonging drugs: avoid combination.
  • Pregnancy and lactation: use only if benefits outweigh risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Moxifloxacin can interact with several medications.

Major Interactions (Avoid)

  • Co‑administration with other fluoroquinolones: increased toxicity.
  • Concurrent use with QT‑prolonging drugs (e.g., quinidine, macrolides): risk of cardiac arrhythmia.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may reduce antibacterial activity.
  • Antacids containing aluminum or magnesium: may impair absorption.
  • Warfarin: may enhance anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: increased risk of tendon rupture.
  • Theophylline: may increase plasma levels.
  • Cyclosporine: potential for increased toxicity.

Frequently Asked Questions

Moxifloxacin Teva is an intravenous fluoroquinolone antibiotic used to treat serious bacterial infections, including community‑acquired pneumonia, intra‑abdominal infections, skin and soft‑tissue infections, and acute exacerbations of chronic bronchitis.

Moxifloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This blockade prevents bacterial cell division, leading to bacterial death and resolution of the infection.

The dose of Moxifloxacin Teva is determined by the prescribing clinician based on the type and severity of infection, patient weight, renal function, and other clinical factors. No fixed regimen is provided here.

Safety data for Moxifloxacin during pregnancy and lactation are limited. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required), and import documentation.

Moxifloxacin offers a broader spectrum against Gram‑positive organisms and better activity in respiratory infections compared with older fluoroquinolones such as ciprofloxacin. It also has a longer half‑life, allowing once‑daily dosing, but shares class‑related safety considerations like QT prolongation and tendon toxicity.

The product must be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Use aseptic techniques when preparing the injection, and discard any solution that appears discolored or contains particles.

Moxifloxacin Teva is administered intravenously by a healthcare professional. The solution is typically diluted in an appropriate compatible IV fluid and infused over a prescribed period, usually 30‑60 minutes, under aseptic conditions.

Serious risks include tendon rupture, QT interval prolongation leading to potentially fatal arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and hepatic failure. Patients should be monitored closely for any signs of these events.

Moxifloxacin Teva should be avoided in patients with known hypersensitivity to fluoroquinolones, a history of tendon disorders related to fluoroquinolone use, uncontrolled QT prolongation, or those taking other medications that significantly prolong the QT interval. Caution is also advised in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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