Product image of Moxifloxacina Rompharm (Moxifloxacin Hydrochloride) supplied by GNH India

Moxifloxacina Rompharm

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Moxifloxacina Rompharm (Moxifloxacin Hydrochloride)

Moxifloxacin Hydrochloride, the active ingredient in Moxifloxacina Rompharm, is a fluoroquinolone antibiotic presented as an ophthalmic preparation for ocular use. It treats bacterial conjunctivitis, bacterial keratitis and other susceptible ocular bacterial infections in patients requiring topical therapy.

GNH India supplies Moxifloxacina Rompharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

S.C. Rompharm Company S.R.L.

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Indications & Clinical Uses

Moxifloxacina Rompharm is a fluoroquinolone antibiotic used to manage bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces bacterial load and resolves infection of the conjunctiva.
  • Bacterial keratitis: eradicates causative organisms and promotes corneal healing.
  • Other susceptible ocular bacterial infections: provides broad‑spectrum antibacterial activity for various eye infections.

How It Works

  • Moxifloxacin hydrochloride inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By blocking these targets, the drug prevents bacterial cell division and leads to bacterial cell death, delivering a bactericidal effect against susceptible ocular pathogens.

Side Effects

Moxifloxacina Rompharm may cause ocular and systemic adverse reactions.

Common Side Effects

  • Burning or stinging sensation upon instillation.
  • Redness of the eye.
  • Tearing or increased lacrimation.
  • Foreign body sensation.
  • Blurred vision.
  • Mild itching.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Toxic anterior segment syndrome.
  • Corneal ulceration or perforation.
  • Vision loss.
  • Systemic hypersensitivity reactions.

Precautions & Warnings

Before prescribing Moxifloxacina Rompharm, consider the following precautions.

  • Allergy assessment: confirm no known hypersensitivity to fluoroquinolones.
  • Pregnancy and lactation: use only if benefits outweigh potential risks; data are limited.
  • Contact lens wearers: remove lenses before administration and avoid re‑insertion until after dosing.
  • Concomitant ocular medications: avoid simultaneous use unless directed by a clinician.
  • Monitor for systemic fluoroquinolone effects such as tendonitis or CNS disturbances.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Moxifloxacina Rompharm can interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: concurrent use may increase systemic exposure and toxicity.
  • Corticosteroid eye drops: may raise the risk of corneal perforation.
  • Anticholinergic agents: may reduce ocular absorption of the antibiotic.

Moderate Interactions (Monitor Closely)

  • Nonsteroidal anti‑inflammatory eye drops: may affect corneal healing.
  • Herbal supplements containing quinine: potential additive toxicity.
  • Other ophthalmic antibiotics: assess for additive ocular toxicity.

Frequently Asked Questions

Moxifloxacina Rompharm is an ophthalmic fluoroquinolone antibiotic indicated for the treatment of bacterial conjunctivitis, bacterial keratitis, and other susceptible ocular bacterial infections. It is applied topically to the eye to eradicate the causative bacteria and promote healing.

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these targets, the drug prevents bacterial cell division, leading to a bactericidal effect that clears the infection in ocular tissues.

The dosing regimen for Moxifloxacina Rompharm is determined by the prescribing clinician based on the specific infection, severity, and patient factors. The prescriber will provide detailed instructions on the number of drops, frequency, and duration of therapy.

Safety data for Moxifloxacina Rompharm in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Moxifloxacina Rompharm belongs to the fluoroquinolone class, offering broad‑spectrum activity against Gram‑positive and Gram‑negative ocular pathogens. Compared with older agents such as ciprofloxacin, it often provides enhanced potency, better tissue penetration, and a reduced dosing frequency, though choice depends on local resistance patterns and clinician preference.

Store the product at room temperature, preferably below 25 °C, in its original container. Protect it from direct light and moisture. Do not freeze. Ensure the vial or bottle is tightly sealed when not in use to maintain sterility.

Moxifloxacina Rompharm is administered as eye drops. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. Avoid touching the tip of the container to the eye or any surface.

Serious risks include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, toxic anterior segment syndrome, corneal ulceration or perforation, and vision loss. Patients should be instructed to seek immediate medical attention if they experience signs of a severe reaction.

Individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any component of the formulation should not use the product. Caution is also advised for patients with a history of tendon disorders, severe renal impairment, or those taking systemic fluoroquinolones without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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