Product image of Moxifloxacine Eg (Moxifloxacin) supplied by GNH India

Moxifloxacine Eg

Active Ingredient:
Moxifloxacin
Origin:
EU

Moxifloxacine Eg (Moxifloxacin)

Moxifloxacin, the active ingredient in Moxifloxacine Eg, is a fluoroquinolone presented as a tablet for oral use. It treats a range of bacterial infections in adults, including pneumonia, sinusitis and bronchitis.
GNH India supplies Moxifloxacine Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Moxifloxacine Eg is a fluoroquinolone antibacterial used to treat several serious bacterial infections.

  • Community‑acquired bacterial pneumonia: eradicates the causative pathogens and improves respiratory function.
  • Acute bacterial sinusitis: reduces sinus inflammation and clears infection.
  • Acute bacterial exacerbation of chronic bronchitis: shortens symptom duration and prevents complications.
  • Skin and skin structure infections: eliminates skin‑resident bacteria and promotes healing.
  • Intra‑abdominal infections: targets mixed bacterial flora to resolve intra‑abdominal sepsis.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By blocking these targets, the drug prevents bacterial DNA synthesis and transcription, leading to bacterial cell death and a bactericidal effect against a broad spectrum of Gram‑positive and Gram‑negative organisms.

Side Effects

Moxifloxacine Eg may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Rash: skin redness or itching.
  • Photosensitivity: increased skin reaction to sunlight.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or swelling, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Hepatotoxicity: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Before prescribing Moxifloxacine Eg, clinicians should consider several safety measures.

  • Assess renal function: adjust therapy if renal impairment is present.
  • Monitor for tendon pain: discontinue if signs of tendonitis or rupture appear.
  • Check QT interval: avoid in patients with known prolonged QT or electrolyte disturbances.
  • Avoid use in pregnancy Category C unless benefits outweigh risks.
  • Avoid concomitant use with other QT‑prolonging agents.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Moxifloxacine Eg can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce drug absorption.
  • Warfarin: increase anticoagulant effect and bleeding risk.
  • Theophylline: elevate serum theophylline concentrations.

Moderate Interactions (Monitor Closely)

  • Ciprofloxacin: additive QT‑prolongation effect.
  • NSAIDs: heightened risk of central nervous system adverse events.
  • Oral contraceptives: possible reduction in contraceptive efficacy.

Frequently Asked Questions

Moxifloxacine Eg contains moxifloxacin, a fluoroquinolone antibacterial indicated for community‑acquired bacterial pneumonia, acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, skin and skin‑structure infections, and intra‑abdominal infections. It is prescribed for adult patients when a broad‑spectrum oral antibiotic is required.

Moxifloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes needed for DNA replication and transcription. By inhibiting these targets, the drug prevents bacterial DNA synthesis, leading to rapid bacterial cell death and a bactericidal effect against many Gram‑positive and Gram‑negative organisms.

The specific dose and duration of Moxifloxacine Eg are determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors. The prescriber will select the appropriate regimen from the product labeling.

Moxifloxacine Eg is classified as Pregnancy Category C, meaning risk cannot be ruled out. It should only be used if the potential benefit justifies the potential risk to the fetus. Limited data are available for breastfeeding; a decision should be made by the healthcare provider after weighing benefits and risks.

To order Moxifloxacine Eg, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any required import documentation.

Moxifloxacine Eg (moxifloxacin) offers a broader spectrum against Gram‑positive organisms and better activity against atypical pathogens compared with older fluoroquinolones such as ciprofloxacin. It also has a longer half‑life, allowing once‑daily dosing, but shares class‑related safety considerations like QT prolongation and tendon toxicity.

Moxifloxacine Eg should be stored at temperatures below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Do not store in a bathroom or near a heat source, and keep the container tightly closed when not in use.

Moxifloxacine Eg is administered orally, usually as a tablet taken with a full glass of water. It may be taken with or without food, but antacids containing aluminum or magnesium should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture, especially in the Achilles tendon; QT interval prolongation leading to cardiac arrhythmias; severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome; Clostridioides difficile‑associated colitis; and potential liver injury. Patients should be monitored for these events and advised to seek immediate medical attention if they occur.

Moxifloxacine Eg should be avoided in patients with a known hypersensitivity to moxifloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, individuals with prolonged QT interval or uncontrolled electrolyte disturbances, and pregnant women unless the benefit outweighs the risk. Clinicians should assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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