Product image of Moxifloxacine Eg (Moxifloxacin Hydrochloride) supplied by GNH India

Moxifloxacine Eg

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Moxifloxacine Eg (Moxifloxacin Hydrochloride)

Moxifloxacin, the active ingredient in Moxifloxacine Eg, is a fluoroquinolone presented as an oral tablet for systemic use. It treats a range of bacterial infections, including community‑acquired pneumonia, acute bacterial sinusitis, and exacerbations of chronic bronchitis in adult patients, and is also indicated for skin and soft‑tissue infections and intra‑abdominal infections.

GNH India supplies Moxifloxacine Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU GMP standards and providing full traceability from manufacturing to delivery.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Moxifloxacin is a fluoroquinolone antibacterial used to treat several common bacterial infections.

  • Community‑acquired bacterial pneumonia: eradicates the causative pathogens and improves respiratory function.
  • Acute bacterial sinusitis: reduces sinus inflammation and clears infection.
  • Acute bacterial exacerbation of chronic bronchitis: controls bacterial load and alleviates cough.
  • Skin and skin structure infections: eliminates skin‑associated bacteria and promotes healing.
  • Intra‑abdominal infections: targets mixed bacterial flora to resolve abdominal infection.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By blocking these targets, the drug prevents bacterial DNA synthesis, leading to bactericidal activity against susceptible Gram‑positive and Gram‑negative organisms.

Side Effects

Moxifloxacin may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Abdominal pain: cramping or discomfort.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or swelling, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Clostridioides difficile colitis: severe diarrhea with abdominal pain.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: numbness or tingling in extremities.

Precautions & Warnings

Before prescribing moxifloxacin, clinicians should consider several safety measures.

  • Assess renal function: adjust therapy if significant impairment exists.
  • Monitor for tendon pain: discontinue if signs of tendonitis or rupture appear.
  • Check cardiac status: avoid in patients with known QT‑prolongation risk.
  • Avoid use in patients with known hypersensitivity to fluoroquinolones.
  • Store at room temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Moxifloxacin can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: reduce moxifloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Other QT‑prolonging drugs: heightened risk of cardiac arrhythmias.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs: may increase central nervous system side effects.
  • Corticosteroids: may raise the risk of tendon rupture.
  • CYP450 inhibitors (e.g., fluconazole): may elevate moxifloxacin plasma concentrations.

Frequently Asked Questions

Moxifloxacine Eg contains moxifloxacin, a fluoroquinolone antibacterial indicated for community‑acquired bacterial pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, skin and soft‑tissue infections, and intra‑abdominal infections caused by susceptible bacteria.

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. This blockade stops bacterial DNA synthesis, leading to rapid bactericidal activity against a broad spectrum of Gram‑positive and Gram‑negative organisms.

The specific dose and duration of Moxifloxacine Eg are determined by the prescribing clinician based on the infection type, severity, patient age, renal function and other clinical factors. Patients should follow the prescriber’s instructions exactly.

The safety of moxifloxacin in pregnancy and lactation has not been definitively established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To request Moxifloxacine Eg, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Moxifloxacin offers broad‑spectrum coverage, including atypical pathogens, and can be administered once daily orally, which may simplify therapy compared with some beta‑lactams that require multiple daily doses or intravenous administration. Choice of therapy should consider local resistance patterns, patient allergies and clinical guidelines.

Moxifloxacine Eg should be stored at room temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat and direct sunlight to maintain stability and potency.

Moxifloxacine Eg is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concurrent intake of antacids containing magnesium or aluminum, as these may reduce absorption.

Serious risks include tendon rupture (especially in the Achilles), QT interval prolongation leading to arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, hepatic injury, and peripheral neuropathy. Patients should be advised to seek immediate medical attention if any of these occur.

Moxifloxacine Eg is contraindicated in individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any component of the formulation. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone use or those with significant QT prolongation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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