Product image of Moxifloxacine Teva (Moxifloxacin) supplied by GNH India

Moxifloxacine Teva

Active Ingredient:
Moxifloxacin
Origin:
EU

Moxifloxacine Teva (Moxifloxacin)

Moxifloxacin, the active ingredient in Moxifloxacine Teva, is a fluoroquinolone presented as an oral tablet for oral use. It treats a range of bacterial infections, including community‑acquired pneumonia, sinusitis, bronchitis exacerbations, skin infections, and intra‑abdominal infections in adult patients.

GNH India supplies Moxifloxacine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

  • Moxifloxacine Teva is a fluoroquinolone antibacterial indicated for several bacterial infection categories.
  • Community‑acquired pneumonia: effective treatment of susceptible bacterial pathogens in adults.
  • Acute bacterial sinusitis: eradicates causative organisms to relieve sinus inflammation.
  • Acute exacerbation of chronic bronchitis: reduces bacterial load during flare‑ups.
  • Skin and skin‑structure infections: combats Gram‑positive and Gram‑negative bacteria.
  • Complicated intra‑abdominal infections: aids in controlling mixed bacterial flora.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents the unwinding and resealing of DNA strands, leading to bacterial cell death and suppression of infection.

Side Effects

Moxifloxacine Teva may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Abdominal discomfort
  • Rash

Serious or Rare Side Effects

  • Tendon rupture or inflammation
  • QT interval prolongation leading to cardiac arrhythmia
  • Clostridioides difficile‑associated colitis
  • Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome)
  • Hepatic dysfunction
  • Peripheral neuropathy

Precautions & Warnings

  • Before prescribing Moxifloxacine Teva, clinicians should consider several safety factors.
  • Renal impairment: adjust therapy based on renal function.
  • History of tendon disorders: avoid use due to risk of tendon rupture.
  • QT prolongation risk: monitor ECG in patients with cardiac risk factors.
  • Concomitant corticosteroids: increased risk of tendon injury.
  • Pregnancy and lactation: use only if potential benefits outweigh risks.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Moxifloxacine Teva can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Other fluoroquinolones: additive toxicity.
  • Antacids containing magnesium or aluminum: markedly reduce absorption.
  • Warfarin: increased anticoagulant effect and bleeding risk.

Moderate Interactions (Monitor Closely)

  • NSAIDs: heightened risk of central nervous system stimulation.
  • Theophylline: elevated plasma concentrations.
  • Cyclosporine: increased cyclosporine levels, requiring dose adjustment.

Frequently Asked Questions

Moxifloxacine Teva is indicated for adult patients with community‑acquired pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, skin and skin‑structure infections, and complicated intra‑abdominal infections caused by susceptible bacteria.

Moxifloxacin blocks bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes required for DNA replication and transcription. This inhibition prevents bacterial cells from reproducing, leading to bacterial death and resolution of the infection.

The dosage regimen for Moxifloxacine Teva is determined by the prescribing clinician based on the specific infection, patient characteristics, and local guidelines. Patients should follow the prescriber’s instructions and not alter the dose on their own.

The pregnancy safety category for moxifloxacin is not definitively established. It should be used during pregnancy or lactation only when the potential benefit justifies the potential risk to the fetus or infant, and after careful clinical assessment.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Moxifloxacine Teva offers a broader spectrum against Gram‑positive organisms and better activity in respiratory infections compared with some older fluoroquinolones such as ciprofloxacin. However, safety considerations like QT prolongation and tendon risk are similar across the class, so choice depends on infection type and patient risk factors.

Store the tablets at ambient temperature, preferably below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat, and direct sunlight to maintain potency throughout the shelf life.

Moxifloxacine Teva is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concurrent intake of antacids containing magnesium or aluminum, which may interfere with absorption.

Serious adverse events include tendon rupture or tendinitis, QT interval prolongation that may lead to arrhythmias, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, Clostridioides difficile‑associated colitis, and hepatic or peripheral nerve toxicity.

Patients with a known hypersensitivity to moxifloxacin or any fluoroquinolone should avoid the drug. It is also contraindicated in individuals with a history of tendon disorders related to fluoroquinolone use, those with significant QT prolongation, and patients with uncontrolled epilepsy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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