Product image of Moxifloxacino Cinfa (Moxifloxacin Hydrochloride) supplied by GNH India

Moxifloxacino Cinfa

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Moxifloxacino Cinfa (Moxifloxacin Hydrochloride)

Moxifloxacin Hydrochloride, the active ingredient in Moxifloxacino Cinfa, is a fluoroquinolone antibiotic presented as an oral tablet for systemic use. It treats a range of bacterial infections, including respiratory, sinus, skin and intra‑abdominal infections, in adult patients. It is indicated for community‑acquired bacterial pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, skin and skin structure infections, and intra‑abdominal infections in appropriate patients.

GNH India supplies Moxifloxacino Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Moxifloxacino Cinfa is a fluoroquinolone antibiotic used to treat bacterial infections in several organ systems.

  • Community‑acquired bacterial pneumonia: eradicates susceptible pathogens causing lower‑respiratory‑tract infection.
  • Acute bacterial sinusitis: clears infection of the paranasal sinuses.
  • Acute exacerbations of chronic bronchitis: reduces bacterial load during flare‑ups.
  • Skin and skin structure infections: treats cellulitis, abscesses and other soft‑tissue infections.
  • Intra‑abdominal infections: combats mixed‑flora infections within the abdominal cavity.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription and repair. By stabilizing the enzyme‑DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal activity is broad‑spectrum, covering many Gram‑positive, Gram‑negative and atypical organisms.

Side Effects

Moxifloxacino Cinfa may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Rash
  • Abdominal pain

Serious or Rare Side Effects

  • Tendon rupture or tendinitis
  • QT interval prolongation leading to cardiac arrhythmia
  • Severe allergic reactions (e.g., Stevens‑Johnson syndrome)
  • Clostridioides difficile‑associated colitis
  • Hepatic dysfunction
  • Peripheral neuropathy

Precautions & Warnings

Before prescribing Moxifloxacino Cinfa, clinicians should consider several safety factors.

  • Renal impairment: assess kidney function and adjust dose if necessary.
  • History of tendon disorders: avoid use in patients with prior tendon injury.
  • Cardiac risk: monitor ECG in patients with known QT prolongation or electrolyte disturbances.
  • Pregnancy and lactation: use only when benefits outweigh potential risks.
  • Concomitant medications: review for drugs that may increase toxicity or reduce efficacy.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Moxifloxacino Cinfa can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: reduce oral absorption of moxifloxacin.
  • Systemic corticosteroids: increase risk of tendon rupture.
  • Warfarin: may enhance anticoagulant effect, requiring INR monitoring.

Moderate Interactions (Monitor Closely)

  • Other fluoroquinolones: additive risk of QT prolongation.
  • Theophylline: moxifloxacin can raise plasma theophylline levels.
  • Cyclosporine: increased risk of nephrotoxicity when combined.

Frequently Asked Questions

Moxifloxacino Cinfa is indicated for adult patients with community‑acquired bacterial pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, skin and skin‑structure infections, and intra‑abdominal infections caused by susceptible bacteria. The drug targets a broad spectrum of Gram‑positive, Gram‑negative and atypical organisms, making it suitable for these common bacterial conditions.

Moxifloxacin, the active ingredient in Moxifloxacino Cinfa, blocks bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By inhibiting them, the drug prevents bacterial DNA from unwinding and resealing, leading to lethal DNA breaks and bacterial cell death.

The exact dose of Moxifloxacino Cinfa is determined by the prescribing clinician based on the specific infection, patient age, weight, renal function and local guidelines. Healthcare professionals select the appropriate strength and duration to achieve optimal therapeutic outcomes while minimizing risk.

Safety data for moxifloxacin in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and after careful consideration by the prescriber.

To request Moxifloxacino Cinfa, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Moxifloxacin offers a broader spectrum against atypical respiratory pathogens and has a once‑daily dosing schedule, which can improve adherence compared with some older fluoroquinolones. Its pharmacokinetic profile provides higher lung tissue concentrations, making it especially useful for respiratory infections, while sharing the class‑related safety considerations of fluoroquinolones.

Moxifloxacino Cinfa tablets should be stored at temperatures below 25 °C (77 °F). Keep them in the original blister pack or container, protect from moisture, heat and direct sunlight, and ensure the packaging remains tightly closed until use.

Moxifloxacino Cinfa is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid concurrent intake of antacids containing magnesium or aluminum, as these can lower absorption. The tablet should be swallowed whole and not chewed or crushed.

Serious adverse events include tendon rupture or tendinitis, QT‑interval prolongation that may lead to cardiac arrhythmias, severe hypersensitivity reactions such as Stevens‑Johnson syndrome, Clostridioides difficile‑associated colitis, hepatic injury and peripheral neuropathy. Patients should be educated to report any sudden joint pain, palpitations, rash or persistent diarrhea promptly.

Moxifloxacino Cinfa is contraindicated in patients with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any of the tablet’s excipients. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone use, uncontrolled arrhythmias, or those taking medications that significantly prolong the QT interval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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