Product image of Moxifloxacino Tevagen (Moxifloxacin) supplied by GNH India

Moxifloxacino Tevagen

Active Ingredient:
Moxifloxacin
Origin:
EU

Moxifloxacino Tevagen (Moxifloxacin)

Moxifloxacin, the active ingredient in Moxifloxacino Tevagen, is a fluoroquinolone antibiotic presented as an oral dosage form for systemic use. It treats a range of serious bacterial infections in adults and children when prescribed by a qualified healthcare professional.

GNH India supplies Moxifloxacino Tevagen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

Moxifloxacin is a broad‑spectrum fluoroquinolone used to treat bacterial infections affecting various organ systems.

  • Community‑acquired bacterial pneumonia: eradicates susceptible pathogens, improving respiratory function and reducing fever.
  • Acute bacterial sinusitis: clears sinus infection, relieving congestion and facial pain.
  • Acute bacterial exacerbation of chronic bronchitis: reduces bacterial load, aiding recovery of lung function.
  • Skin and skin structure infections: eliminates causative bacteria, promoting wound healing.
  • Intra‑abdominal infections: treats mixed‑organism infections, supporting resolution of abdominal pain and systemic signs.

How It Works

  • Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these targets, it prevents bacterial DNA supercoiling and separation, leading to halted cell division and bacterial cell death. This bactericidal action is effective against a wide range of Gram‑positive and Gram‑negative organisms.

Side Effects

Moxifloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain and loss of function, especially in the Achilles tendon.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Severe allergic reaction: anaphylaxis with swelling, breathing difficulty.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Peripheral neuropathy: tingling or numbness in extremities.

Precautions & Warnings

Before prescribing moxifloxacin, consider patient‑specific factors and safety measures.

  • Pregnancy: category C; use only if potential benefits justify potential fetal risk.
  • Renal impairment: assess kidney function; dose adjustment may be required.
  • History of tendon disorders: avoid use due to increased risk of tendon rupture.
  • Concomitant QT‑prolonging drugs: monitor ECG and electrolytes closely.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Moxifloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce moxifloxacin absorption.
  • Corticosteroids: increase risk of tendon rupture.
  • Warfarin: may enhance anticoagulant effect, raising bleeding risk.

Moderate Interactions (Monitor Closely)

  • Theophylline: may increase serum theophylline concentrations.
  • Cyclosporine: may raise moxifloxacin plasma levels, requiring monitoring.

Frequently Asked Questions

Moxifloxacino Tevagen, containing moxifloxacin, is prescribed for a range of bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, skin and soft‑tissue infections, and intra‑abdominal infections caused by susceptible organisms.

Moxifloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By inhibiting these targets, it prevents bacterial cells from multiplying, leading to bacterial death and resolution of the infection.

The dosage of Moxifloxacino Tevagen is determined by the prescribing clinician based on the specific infection, patient age, weight, renal function, and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Moxifloxacino Tevagen is classified as pregnancy category C, meaning it should be used only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should discuss risks and alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Moxifloxacin offers a broader spectrum against Gram‑positive organisms and better activity in respiratory infections compared with older fluoroquinolones like ciprofloxacin. It also has a more favorable dosing schedule, often once daily, but shares class‑related safety considerations such as tendon risk and QT prolongation.

Moxifloxacino Tevagen should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and potency throughout its shelf life.

Moxifloxacino Tevagen is administered orally, typically as a tablet or oral suspension, depending on the marketed formulation. It should be taken with a full glass of water, and patients may be advised to avoid taking it with antacids that contain aluminum or magnesium.

Serious risks include tendon rupture, especially in the Achilles tendon, QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhea, and potential hepatic or neurological adverse events. Patients should seek immediate medical attention if they experience any of these symptoms.

Moxifloxacino Tevagen should be avoided in patients with a known hypersensitivity to moxifloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, individuals taking other QT‑prolonging agents without monitoring, and patients with certain cardiac conditions where QT prolongation poses a high risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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