Product image of Moxivig (Moxifloxacin Hydrochloride) supplied by GNH India

Moxivig

Active Ingredient:
Moxifloxacin Hydrochloride
Origin:
EU

Moxivig (Moxifloxacin Hydrochloride)

Moxifloxacin Hydrochloride, the active ingredient in Moxivig, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial eye infections such as conjunctivitis and keratitis in adult and pediatric patients by inhibiting bacterial DNA replication, leading to rapid bacterial clearance.

GNH India supplies Moxivig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Novartis Ireland Limited

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Indications & Clinical Uses

Moxivig is indicated for bacterial infections of the eye, targeting common ocular pathogens.

  • Bacterial conjunctivitis: reduces bacterial load and speeds symptom relief in acute conjunctival infection.
  • Bacterial keratitis: eradicates pathogenic bacteria in corneal ulcers, promoting healing.
  • Post‑operative ocular infection prophylaxis: prevents bacterial colonisation after eye surgery, reducing postoperative infection risk.

How It Works

  • Moxifloxacin Hydrochloride inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By blocking these targets, the drug prevents bacterial DNA synthesis, leading to cell death and effective eradication of susceptible ocular pathogens.

Side Effects

Moxivig may cause ocular and systemic adverse reactions.

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Tearing or increased lacrimation.
  • Foreign body sensation.
  • Blurred vision.
  • Mild headache.

Serious or Rare Side Effects

  • Allergic reactions such as swelling, rash, or anaphylaxis.
  • Corneal ulceration or thinning.
  • Severe ocular inflammation or uveitis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Systemic hypersensitivity reactions.
  • Vision loss if severe complications develop.

Precautions & Warnings

Before prescribing Moxivig, consider patient‑specific factors and safety measures.

  • Allergy assessment: avoid in patients with known fluoroquinolone hypersensitivity.
  • Contact lens wearers: remove lenses before instillation and avoid re‑wearing until after treatment.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation.
  • Drug interactions: avoid concurrent use with other ophthalmic antibiotics unless directed.
  • Monitoring: watch for worsening infection or signs of severe ocular reaction.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Moxivig can interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: additive risk of tendon toxicity.
  • Topical corticosteroids: may mask infection progression.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: may reduce drug absorption.
  • Non‑steroidal anti‑inflammatory eye drops: may increase local irritation.
  • Other ophthalmic antibiotics: potential antagonism or reduced efficacy.

Frequently Asked Questions

Moxivig is a prescription ophthalmic solution containing moxifloxacin hydrochloride. It is used to treat bacterial eye infections such as acute bacterial conjunctivitis, bacterial keratitis, and to prevent infection after ocular surgery.

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these targets, the drug stops bacterial cell division, leading to rapid bacterial death and clearance of the infection.

The dosing regimen for Moxivig is determined by the prescribing clinician based on the specific infection, severity, and patient factors. The prescriber will specify the number of drops, frequency, and duration of therapy.

Safety data for ocular moxifloxacin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To request Moxivig, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Moxivig belongs to the fluoroquinolone class, offering broad‑spectrum activity against Gram‑positive and Gram‑negative ocular pathogens. Compared with older agents such as ciprofloxacin or ofloxacin, moxifloxacin provides enhanced potency, better corneal penetration, and a convenient dosing schedule, though choice depends on local resistance patterns and physician preference.

Store Moxivig at room temperature, below 25 °C, in its original container. Protect the solution from light and moisture, and keep the cap tightly closed when not in use to maintain sterility.

Moxivig is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption.

Serious risks include severe allergic reactions (e.g., anaphylaxis), corneal ulceration or thinning, and rare systemic hypersensitivity such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience swelling, rash, worsening pain, vision changes, or any signs of severe ocular inflammation.

Moxivig should not be used by individuals with a known hypersensitivity to moxifloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated in patients with active viral or fungal eye infections, as it does not treat these conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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