Product image of Ms Contin (Morphine Sulfate) supplied by GNH India

Ms Contin

Active Ingredient:
Morphine Sulfate
Origin:
EU

Ms Contin (Morphine Sulfate)

Morphine sulfate, the active ingredient in Ms Contin, is an opioid analgesic presented as an extended‑release oral tablet for oral use. It treats moderate to severe acute pain, chronic cancer pain, and severe postoperative pain in adult patients.

GNH India supplies Ms Contin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and specialty clinics worldwide.

Manufacturer / TM Owner

Mundipharma Bv

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ms Contin is an opioid analgesic used to manage pain that originates from severe nociceptive pathways.

  • Moderate to severe acute pain: provides sustained analgesia for short‑term severe pain episodes.
  • Chronic cancer pain: offers continuous pain control for patients with malignant disease.
  • Severe postoperative pain: maintains opioid levels to control pain after major surgery.

How It Works

  • Morphine sulfate acts as a full agonist at μ‑opioid receptors in the central nervous system. Activation of these receptors inhibits ascending pain pathways, alters the perception of pain, and increases pain tolerance. The drug also reduces the release of neurotransmitters involved in nociception, resulting in prolonged analgesic effect when delivered in an extended‑release formulation.

Side Effects

Common Side Effects

  • Nausea: feeling of sickness or urge to vomit.
  • Constipation: reduced bowel movements and hard stools.
  • Drowsiness: increased sleepiness or fatigue.
  • Dry mouth: reduced salivation leading to a parched feeling.

Serious or Rare Side Effects

  • Respiratory depression: slowed or shallow breathing that can be life‑threatening.
  • Severe hypotension: marked drop in blood pressure causing dizziness or fainting.
  • Dependence or addiction: development of physical or psychological reliance on the drug.
  • Anaphylaxis: rare severe allergic reaction with hives, swelling, and airway compromise.

Precautions & Warnings

Ms Contin requires careful clinical oversight to ensure safe use.

  • Assess pain level: evaluate severity and type before initiating therapy.
  • Monitor respiratory function: watch for signs of slowed breathing, especially after dose adjustments.
  • Evaluate opioid tolerance: consider prior opioid exposure when selecting dose.
  • Avoid concurrent CNS depressants: limit use with benzodiazepines, barbiturates, or alcohol.
  • Adjust dose in renal/hepatic impairment: reduce dose or increase monitoring in patients with organ dysfunction.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ms Contin may interact with several drug classes, requiring vigilance.

Major Interactions (Avoid)

  • Other opioids: additive respiratory depression.
  • Central nervous system depressants (e.g., benzodiazepines): increased sedation and respiratory risk.
  • Monoamine oxidase inhibitors (MAOIs): risk of severe hypotension.
  • Alcohol: potentiates sedative effects.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., erythromycin, ketoconazole): may raise morphine levels.
  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce analgesic effect.

Frequently Asked Questions

Ms Contin is an extended‑release oral tablet containing morphine sulfate. It is prescribed to provide long‑lasting relief for moderate to severe acute pain, chronic cancer‑related pain, and severe postoperative pain when continuous opioid therapy is required.

Morphine sulfate binds to μ‑opioid receptors in the brain and spinal cord, inhibiting the transmission of pain signals. This receptor activation reduces the perception of pain and increases the pain threshold, producing analgesia that lasts for several hours with the extended‑release formulation.

The dose of Ms Contin is individualized by the prescribing clinician. Factors such as the intensity of pain, prior opioid exposure, patient age, renal and hepatic function, and concurrent medications guide the selection of an appropriate dose and dosing interval.

Safety data for morphine sulfate in pregnancy and lactation are limited. Because opioids can cross the placenta and enter breast milk, Ms Contin should only be used during pregnancy or while breastfeeding if the potential benefit justifies the potential risk and after thorough discussion with a healthcare professional.

To request Ms Contin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Ms Contin provides a controlled, extended‑release delivery of morphine over 12‑24 hours, reducing the need for frequent dosing compared with immediate‑release morphine, which peaks quickly and requires multiple daily doses. The extended‑release form offers more stable plasma concentrations, which can improve pain control and convenience for chronic pain management.

Ms Contin tablets should be stored at ambient temperature, below 25 °C, in their original container to protect them from moisture and light. Keep the product out of reach of children and do not use tablets that are discolored, broken or past their expiration date.

Ms Contin is taken orally as a whole tablet; it must be swallowed whole with water and not chewed, crushed, or split. The extended‑release matrix is designed to release morphine slowly, and altering the tablet can lead to rapid release and increased risk of overdose.

The most serious risks associated with Ms Contin include respiratory depression, severe hypotension, profound sedation, opioid dependence or addiction, and rare allergic reactions such as anaphylaxis. Patients and caregivers should be alert for shallow breathing, extreme drowsiness, fainting, or signs of an allergic response and seek immediate medical attention if they occur.

Ms Contin should be avoided in individuals with known hypersensitivity to morphine or any component of the tablet, severe respiratory depression, acute asthma attacks, paralytic ileus, or uncontrolled severe head injury. It is also contraindicated in patients taking MAO inhibitors within 14 days or those with significant hepatic or renal impairment without dose adjustment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.