Product image of Mst 10 (Morphine Sulfate) supplied by GNH India

Mst 10

Active Ingredient:
Morphine Sulfate
Origin:
EU

Mst 10 (Morphine Sulfate)

Morphine Sulfate, the active ingredient in Mst 10, is an opioid analgesic presented as an oral formulation for oral use. It is employed to treat moderate to severe acute pain, postoperative pain, and cancer‑related pain in adult patients.

GNH India supplies Mst 10 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Clients benefit from reliable logistics, comprehensive documentation, and responsive technical support throughout the procurement process.

Manufacturer / TM Owner

Mundipharma Farmacêutica, Lda.

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Indications & Clinical Uses

Morphine sulfate is an opioid analgesic used to manage pain conditions that involve the central nervous system.

  • Moderate to severe acute pain: provides rapid analgesia to reduce pain intensity in acute injury or illness.
  • Postoperative pain: controls pain following surgical procedures, facilitating recovery and mobilization.
  • Cancer pain: alleviates persistent malignant pain, improving quality of life in oncology patients.

How It Works

  • Morphine sulfate binds as an agonist to μ‑opioid receptors in the central nervous system, inhibiting the release of neurotransmitters such as substance P, glutamate and norepinephrine. This receptor activation reduces neuronal excitability and alters pain perception pathways, producing analgesia and sedation while also affecting respiratory and gastrointestinal motility.

Side Effects

Morphine sulfate may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Constipation
  • Drowsiness
  • Dizziness
  • Sweating
  • Dry mouth

Serious or Rare Side Effects

  • Respiratory depression
  • Severe hypotension
  • Anaphylactic or severe allergic reaction
  • Adrenal insufficiency
  • Dependence or addiction
  • QT interval prolongation

Precautions & Warnings

When prescribing morphine sulfate, clinicians should observe several safety measures to minimize risk.

  • Assess pain severity and treatment goals: tailor therapy to individual needs.
  • Evaluate renal and hepatic function: adjust dose in impairment.
  • Monitor respiratory status: watch for signs of depression, especially after dose changes.
  • Use the lowest effective dose for the shortest duration required.
  • Avoid concurrent use with other central nervous system depressants unless medically justified.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Morphine sulfate can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Concurrent use with other opioids: increases risk of respiratory depression and overdose.
  • Benzodiazepines or other CNS depressants: synergistic sedation and respiratory effects.
  • Monoamine oxidase inhibitors (MAOIs): may precipitate severe hypertension or serotonin syndrome.
  • Respiratory depressants such as barbiturates: potentiate respiratory compromise.
  • Alcohol: enhances sedative effects and respiratory risk.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise morphine plasma levels.
  • CYP2D6 inhibitors (e.g., fluoxetine): can affect metabolism of certain opioids.
  • Diuretics: may increase risk of hypotension.
  • Anticholinergic agents: may worsen constipation.
  • Antihistamines: may add to drowsiness.

Frequently Asked Questions

Mst 10 contains morphine sulfate, an opioid analgesic indicated for the relief of moderate to severe acute pain, postoperative pain, and cancer‑related pain in adult patients when non‑opioid therapies are insufficient.

Morphine sulfate acts as an agonist at μ‑opioid receptors in the brain and spinal cord. Activation of these receptors reduces the release of pain‑transmitting neurotransmitters, decreasing neuronal excitability and altering the perception of pain.

The appropriate dose of Mst 10 is determined by the prescribing clinician based on the patient’s pain severity, prior opioid exposure, renal and hepatic function, and individual response. No fixed regimen is provided here.

Safety data for morphine sulfate during pregnancy and lactation are limited. It is generally avoided unless the potential benefit justifies the potential risk to the fetus or infant, and it should be used only under close medical supervision.

To order Mst 10, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Morphine sulfate is a prototypical strong opioid with well‑characterised efficacy and safety profiles. Compared with newer synthetic opioids, it has a longer history of clinical use, predictable pharmacokinetics, and is often less expensive, though individual response and side‑effect risk may vary.

Mst 10 should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and handle it in accordance with local regulations for controlled substances.

Mst 10 is supplied for oral use. The tablets or capsules are taken whole with a full glass of water, unless otherwise directed by a healthcare professional. Swallowing whole ensures proper absorption and reduces the risk of irritation.

The most critical risks include respiratory depression, severe hypotension, profound sedation, dependence or addiction, and rare but serious allergic reactions. Patients should be monitored closely, especially during dose initiation or when combined with other depressant agents.

Mst 10 should be avoided in individuals with known hypersensitivity to morphine or other opioids, severe respiratory insufficiency, uncontrolled asthma, paralytic ileus, or in patients receiving monoamine oxidase inhibitors within 14 days. Use is also contraindicated in neonates and infants unless specifically prescribed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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