Product image of Muciclar (Ambroxol Hydrochloride) supplied by GNH India

Muciclar

Active Ingredient:
Ambroxol Hydrochloride
Origin:
EU

Muciclar (Ambroxol Hydrochloride)

Ambroxol Hydrochloride, the active ingredient in Muciclar, is a mucolytic agent presented as an oral formulation for oral use. It helps reduce mucus viscosity and is used in conditions with excessive respiratory secretions.
GNH India supplies Muciclar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Piam Farmaceutici Spa

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Indications & Clinical Uses

  • Ambroxol Hydrochloride is a mucolytic that acts on respiratory conditions characterized by thickened secretions.
  • Acute bronchitis: improves clearance of mucus and eases cough.
  • Chronic bronchitis: reduces mucus viscosity to facilitate expectoration.
  • Respiratory tract infections with mucus hypersecretion: enhances mucociliary transport and relieves congestion.

How It Works

  • Ambroxol stimulates surfactant production by type II pneumocytes and enhances mucociliary clearance. It reduces mucus viscosity by breaking down glycoprotein cross‑links, thereby facilitating the transport of secretions out of the airways and improving respiratory function.

Side Effects

Ambroxol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Altered taste sensation (metallic or bitter).
  • Nausea or mild gastrointestinal discomfort.
  • Diarrhea or loose stools.
  • Headache.
  • Skin rash or pruritus.

Serious or Rare Side Effects

  • Allergic reactions such as urticaria or angioedema.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Hepatic dysfunction or elevated liver enzymes.
  • Eosinophilia or blood dyscrasias.
  • Anaphylactic shock (rare).

Precautions & Warnings

When using Ambroxol, consider the following precautions.

  • Liver function assessment: monitor hepatic enzymes in patients with pre‑existing liver disease.
  • Renal impairment: adjust use in patients with severe kidney dysfunction.
  • Hypersensitivity: avoid in individuals with known allergy to ambroxol or related compounds.
  • Gastrointestinal tolerance: watch for persistent nausea or abdominal pain.
  • Pregnancy and lactation: safety data are limited; use only if benefit outweighs risk.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ambroxol may interact with other medicines; monitor accordingly.

Major Interactions (Avoid)

  • Concurrent use with other mucolytic agents (e.g., N‑acetylcysteine) may increase risk of bronchospasm.
  • Co‑administration with anticholinergic drugs may diminish mucociliary clearance benefits.

Moderate Interactions (Monitor Closely)

  • Antacids may reduce oral absorption of ambroxol.
  • CYP2D6 inhibitors could raise plasma concentrations.
  • Warfarin therapy may experience altered anticoagulant effect.
  • Beta‑agonists may have additive bronchodilatory effects.
  • Cough suppressants may mask therapeutic cough, reducing clearance.

Frequently Asked Questions

Muciclar contains ambroxol hydrochloride, a mucolytic agent used to thin and loosen thick respiratory secretions. It is indicated for acute and chronic bronchitis and for respiratory tract infections where excessive mucus production impairs breathing and cough effectiveness.

Ambroxol stimulates surfactant production in the lungs and breaks down glycoprotein links within mucus, reducing its viscosity. This enhances mucociliary clearance, allowing secretions to be expelled more easily and improving airway patency.

The dosage of Muciclar is determined by the prescribing healthcare professional based on the patient’s age, condition severity, and overall health status. Patients should follow the specific instructions provided by their prescriber and not adjust the dose on their own.

Safety data for ambroxol during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Muciclar (ambroxol) differs from agents such as N‑acetylcysteine by stimulating surfactant production and having a distinct mechanism that breaks down mucus glycoproteins. Clinical choice depends on factors like patient tolerance, drug interactions, and specific therapeutic goals.

Muciclar should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Maintaining these conditions helps preserve the product’s stability and efficacy throughout its shelf life.

Muciclar is taken orally, usually as a tablet or liquid, according to the prescriber’s instructions. It should be swallowed with water and can be taken with or without food, unless otherwise advised by the healthcare professional.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, skin conditions like Stevens‑Johnson syndrome, and significant liver enzyme elevations indicating hepatic dysfunction. Patients should seek immediate medical attention if they experience any of these symptoms.

Muciclar is contraindicated in individuals with known hypersensitivity to ambroxol or any of its excipients. Caution is also advised for patients with severe liver or kidney disease, and it should be avoided in those for whom the prescriber determines the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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