Product image of Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc) supplied by GNH India

Multibic

Active Ingredient:
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Origin:
EU

Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc)

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium (Calc), the active ingredients in Multibic, are an electrolyte solution presented as an IV solution for haemodialysis and intravenous use. It helps maintain electrolyte and acid‑base balance during renal replacement therapy.

GNH India supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Medical Care Hrvatska D.O.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Multibic is used as an electrolyte replacement fluid in renal replacement therapies and related procedures.

  • Chronic kidney disease undergoing haemodialysis: provides essential electrolytes and buffers to maintain plasma homeostasis.
  • Acute renal failure requiring dialysis: assists in correcting acid‑base disturbances.
  • Intraoperative renal support: used as a dialysate component to manage fluid and electrolyte shifts.

How It Works

  • Multibic delivers bicarbonate, sodium, potassium, magnesium and calcium ions directly into the dialysate or bloodstream, allowing diffusion across the dialysis membrane to correct acid‑base imbalances and replenish electrolytes. The solution’s composition is designed to mirror physiologic plasma concentrations, supporting cellular function during haemodialysis and other renal replacement procedures.

Side Effects

Multibic may be associated with a range of adverse reactions.

Common Side Effects

  • Hypotension: drop in blood pressure during infusion.
  • Electrolyte imbalance (hyperkalemia, hypermagnesemia): elevated serum levels.
  • Metabolic alkalosis: excess bicarbonate effect.
  • Nausea: mild gastrointestinal upset.
  • Headache: transient discomfort.
  • Fever: low‑grade temperature rise.

Serious or Rare Side Effects

  • Severe hyperkalemia leading to cardiac arrhythmia.
  • Anaphylactic reaction: rapid onset of hypersensitivity.
  • Severe hypermagnesemia causing respiratory depression.
  • Volume overload resulting in pulmonary edema.

Precautions & Warnings

When using Multibic, clinicians should observe several safety measures.

  • Assess electrolyte levels before use: baseline labs guide composition adjustments.
  • Monitor acid‑base status: frequent blood gas analysis is recommended.
  • Adjust composition for patient‑specific needs: tailor potassium, calcium and magnesium content.
  • Use with caution in patients with cardiac disease: watch for arrhythmias.
  • Avoid rapid infusion rates: prevent sudden hypotension.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Multibic can interact with other medications that affect electrolyte balance.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics: risk of hyperkalemia.
  • Calcium channel blockers combined with high calcium content: risk of hypercalcemia.
  • Magnesium‑containing antacids: risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: monitor serum potassium.
  • Beta‑blockers: monitor blood pressure during infusion.
  • Other IV electrolyte solutions: adjust dosing to avoid cumulative excess.

Frequently Asked Questions

Multibic is an intravenous electrolyte solution used primarily as a dialysate or replacement fluid during haemodialysis and other renal replacement therapies to maintain electrolyte and acid‑base balance.

The solution supplies bicarbonate, sodium, potassium, magnesium and calcium ions, which diffuse across the dialysis membrane to correct metabolic acidosis, replenish electrolytes, and support normal cellular function during dialysis.

The prescribed volume and composition of Multibic are determined by the treating clinician based on the patient’s laboratory values, dialysis prescription and clinical condition.

Safety of Multibic in pregnancy or lactation has not been established. Use only if the potential benefit justifies any potential risk to the mother or infant, and under specialist supervision.

Enquiries can be submitted on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Multibic offers a balanced electrolyte profile that includes magnesium and calcium, which some standard dialysates lack. This can reduce the need for supplemental electrolytes, but clinicians should compare composition, osmolarity and patient‑specific requirements when selecting a dialysate.

Store Multibic at ambient temperature, preferably below 25 °C. Keep the container sealed, protect from direct sunlight and moisture, and follow any manufacturer‑provided handling instructions.

Multibic is administered intravenously, either as part of the dialysate circuit during haemodialysis or as a direct IV infusion, according to the dialysis prescription and infusion rate set by the healthcare professional.

Serious risks include severe electrolyte disturbances such as hyperkalemia or hypermagnesemia, which can lead to cardiac arrhythmias or respiratory depression, and anaphylactic reactions in susceptible individuals.

Patients with known hypersensitivity to any component of the solution, uncontrolled hyperkalemia, severe hypermagnesemia, or those for whom rapid shifts in electrolyte balance are contraindicated should not receive Multibic.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT