Product image of Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc) supplied by GNH India

Multibic

Active Ingredient:
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Origin:
EU

Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc)

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium, the active ingredients in Multibic, are an electrolyte solution presented as an intravenous solution for haemodialysis use. It provides essential electrolytes and buffering capacity to patients with renal failure undergoing haemodialysis.

GNH India supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

Manufacturer / TM Owner

Fresenius Medical Care Deutschland Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Multibic is used in the dialysis setting to manage electrolyte and acid‑base disturbances associated with renal failure.

  • Renal failure requiring haemodialysis: maintains electrolyte and acid‑base balance during treatment.
  • Electrolyte replacement during dialysis: restores sodium, potassium, calcium and magnesium levels to physiologic ranges.
  • Renal replacement therapy: supports overall dialysis therapy by providing a balanced electrolyte composition.

How It Works

  • Multibic delivers a defined mixture of sodium, potassium, calcium, magnesium and bicarbonate ions directly into the extracorporeal circuit. The solution buffers hydrogen ions, stabilises plasma pH, and replenishes electrolytes lost during ultrafiltration, thereby preserving acid‑base homeostasis and preventing electrolyte derangements during haemodialysis.

Side Effects

Multibic may be associated with transient adverse reactions related to electrolyte shifts and infusion characteristics.

Common Side Effects

  • Mild hypotension during dialysis.
  • Nausea or mild vomiting.
  • Headache.
  • Muscle cramps or tingling sensations.
  • Transient changes in serum electrolyte concentrations.
  • Low‑grade fever.

Serious or Rare Side Effects

  • Severe hyperkalaemia.
  • Severe hypocalcaemia.
  • Anaphylactic or severe allergic reaction.
  • Metabolic alkalosis.
  • Cardiac arrhythmia.
  • Pulmonary oedema.

Precautions & Warnings

When using Multibic, clinicians should observe standard dialysis safety measures and monitor patients closely.

  • Monitor electrolytes: check serum sodium, potassium, calcium and magnesium before and after treatment.
  • Assess acid‑base status: evaluate arterial blood gases to detect over‑correction.
  • Adjust dialysis prescription: tailor dialysate composition based on individual patient needs.
  • Use compatible dialysis fluids: avoid mixing with solutions that may precipitate.
  • Avoid in uncontrolled hyperkalaemia: risk of exacerbating high potassium levels.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Multibic can interact with other agents that affect electrolyte balance or acid‑base status.

Major Interactions (Avoid)

  • Calcium‑containing solutions: may cause hypercalcaemia.
  • High‑potassium fluids: risk of severe hyperkalaemia.
  • Sodium bicarbonate administered concurrently: can lead to metabolic alkalosis.
  • Magnesium supplements: may precipitate hypermagnesemia.
  • Incompatible dialysis fluids: can cause precipitation of salts.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may increase serum potassium.
  • NSAIDs: can impair renal function and alter electrolyte handling.
  • Loop diuretics: affect sodium and potassium balance.
  • Beta‑blockers: influence potassium shifts during dialysis.
  • Anticoagulants used in the circuit: monitor for bleeding while maintaining electrolyte goals.

Frequently Asked Questions

Multibic is an intravenous electrolyte solution used during haemodialysis to replace lost electrolytes and provide buffering capacity. It helps maintain acid‑base balance and electrolyte homeostasis in patients with renal failure who require renal replacement therapy.

The combination of sodium hydrogen carbonate, magnesium chloride, potassium chloride, sodium chloride and calcium delivers essential ions directly into the dialysis circuit. These ions replenish those removed by ultrafiltration, while bicarbonate buffers hydrogen ions to stabilize plasma pH during treatment.

The prescribed volume and concentration of Multibic are determined by the treating physician or dialysis specialist based on the patient’s individual electrolyte and acid‑base requirements. Dosing is customized for each dialysis session.

The safety of Multibic in pregnancy or lactation has not been established. Use should be considered only if the potential benefit justifies any potential risk to the mother or infant, and decisions should be made by the treating clinician.

To request Multibic, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Multibic offers a balanced mix of sodium, potassium, calcium, magnesium and bicarbonate, similar to standard dialysate solutions but formulated as an injectable concentrate. Compared with plain saline or bicarbonate‑only solutions, it provides a more comprehensive electrolyte profile, reducing the need for additional supplementation during dialysis.

Multibic should be stored at 2‑8 °C in a refrigerator, protected from light and never frozen. Keep the container tightly closed and handle with aseptic technique to maintain sterility before use.

Multibic is added to the dialysis circuit as an intravenous solution according to the prescribed volume. It is mixed with the dialysate or administered directly into the extracorporeal blood line under sterile conditions during the haemodialysis session.

Serious risks include severe electrolyte disturbances such as hyperkalaemia, hypocalcaemia, or metabolic alkalosis, as well as rare anaphylactic reactions. These events require immediate medical attention and close monitoring of laboratory values during treatment.

Multibic should be avoided in patients with uncontrolled hyperkalaemia, severe hypercalcaemia, known hypersensitivity to any component, or when incompatible dialysis fluids are being used. Clinicians must assess each patient’s condition before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT