Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc)

Sodium hydrogen carbonate acts as a buffering agent. When infused, it combines with excess hydrogen ions in the blood to form carbonic acid, which is then converted to carbon dioxide and water. This reaction helps correct metabolic acidosis that can develop during dialysis, supporting a stable pH environment for cellular function.

The dose of Multibic is individualized by the prescribing clinician based on the patient’s current electrolyte profile, acid‑base status, dialysis prescription and overall clinical condition. Laboratory values and the specific dialysis modality guide the volume and rate of infusion, and the prescriber sets the exact regimen.

Safety data for Multibic in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians are advised to assess each case carefully and follow local regulatory guidance.

To place an order, submit an enquiry on the Multibic product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Multibic offers a balanced combination of sodium hydrogen carbonate, magnesium, potassium, sodium chloride and calcium, providing both buffering capacity and essential electrolytes in a single formulation. Compared with products that supply only bicarbonate or individual ions, Multibic reduces the need for multiple admixtures, simplifying preparation and helping maintain consistent electrolyte concentrations during treatment.

Multibic should be stored at ambient temperature, preferably below 25 °C. Keep the container sealed in its original packaging, protect it from moisture, direct sunlight and extreme temperature fluctuations. Do not freeze the solution, and inspect the vial for any particulate matter before use.

Multibic is administered intravenously, typically added to the dialysis circuit or infused directly into the patient’s bloodstream according to the dialysis prescription. The solution is mixed aseptically and delivered at a controlled rate that matches the patient’s fluid and electrolyte requirements as determined by the treating nephrologist.

The most serious risks include severe hyperkalemia, which can precipitate life‑threatening cardiac arrhythmias, and metabolic alkalosis from excessive bicarbonate, potentially leading to respiratory compensation issues. Rarely, an anaphylactoid reaction may occur, presenting with hypotension, rash and respiratory distress, requiring immediate medical intervention.

Multibic should be avoided in patients with known hypersensitivity to any of its components, those with severe hyperkalemia, uncontrolled metabolic alkalosis, or conditions where rapid shifts in electrolyte balance could be hazardous, such as certain cardiac arrhythmias. Clinical judgment is essential to determine suitability on a case‑by‑case basis.