Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra)

Sodium hydrogen carbonate (bicarbonate) acts as a systemic buffer. When infused, it combines with hydrogen ions to form carbonic acid, which is then converted to carbon dioxide and water, thereby raising blood pH and correcting metabolic acidosis. This buffering action, together with the supplied electrolytes, supports normal physiological function during dialysis.

The dose of Multibic is individualized by the prescribing clinician based on the patient’s electrolyte profile, acid‑base status, weight and the specific dialysis protocol. Healthcare professionals calculate the required volume and infusion rate to achieve the desired correction, and the exact regimen is documented in the patient’s medical order.

The safety of Multibic in pregnancy or lactation has not been definitively established. Because it contains essential electrolytes and bicarbonate, it may be used when the potential benefit outweighs any unknown risk. The decision should be made by the treating physician in consultation with obstetric specialists.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Multibic. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Multibic differs from standard dialysis fluids by containing a combination of bicarbonate and a balanced electrolyte mix (Na+, Mg2+, Ca2+, Cl‑). This formulation offers simultaneous correction of metabolic acidosis and replenishment of key ions, whereas some alternatives may lack magnesium or calcium, requiring additional supplementation.

Multibic should be stored at 2‑8 °C in a refrigerator. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution. Before use, inspect for particulate matter or discoloration and discard if any abnormalities are observed.

Multibic is administered intravenously, either as a direct infusion during haemodialysis or as a separate intravenous infusion. The solution is typically delivered through a sterile infusion set, with the rate and volume determined by the clinician based on the patient’s clinical parameters and treatment protocol.

Serious risks include severe hypermagnesemia, profound metabolic alkalosis, anaphylactic reactions and cardiac arrhythmias caused by rapid electrolyte shifts. Continuous monitoring of serum electrolytes, blood pH and cardiac rhythm is essential to detect and manage these complications promptly.

Multibic should be avoided in patients with known hypersensitivity to any of its components, in those with uncontrolled hypercalcemia or hypermagnesemia, and in individuals where rapid correction of acid‑base balance could be harmful, such as certain cases of severe respiratory alkalosis. Clinical judgment is required for each patient.