Product image of Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra) supplied by GNH India

Multibic

Active Ingredient:
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra
Origin:
EU

Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra)

Sodium hydrogen carbonate, the active ingredient in Multibic, is an electrolyte solution presented as a solution for injection for intravenous and haemodialysis use. It supplies sodium, chloride, calcium, magnesium ions and a bicarbonate buffer to maintain acid‑base and electrolyte balance during haemodialysis and intravenous electrolyte replacement. Multibic is classified as a renal replacement therapy adjunct and is used in hospitals and dialysis centres for patients requiring precise electrolyte management.

GNH India supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and dialysis clinics worldwide.

Manufacturer / TM Owner

Fresenius Medical Care Deutschland Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Multibic is used as an electrolyte solution in renal replacement therapy and intravenous electrolyte replacement.

  • Haemodialysis fluid: provides balanced sodium, chloride, calcium, magnesium and bicarbonate to maintain acid‑base status during dialysis.
  • Intravenous electrolyte replacement: corrects deficits of key electrolytes in patients receiving IV therapy.
  • Renal replacement therapy adjunct: supports overall electrolyte homeostasis in patients undergoing dialysis procedures.

How It Works

  • Multibic delivers sodium, chloride, calcium, magnesium ions together with bicarbonate, directly increasing plasma concentrations of these electrolytes. The added bicarbonate acts as a buffer, helping to correct metabolic acidosis, while the ions contribute to osmotic balance and electrical neutrality, facilitating proper cellular function during haemodialysis and intravenous electrolyte therapy.

Side Effects

Multibic may cause electrolyte‑related reactions and infusion site responses.

Common Side Effects

  • Hypernatremia: elevated serum sodium levels.
  • Hyperchloremia: increased chloride concentration.
  • Hypercalcemia: excess calcium in blood.
  • Hypermagnesemia: raised magnesium levels.
  • Infusion site irritation: redness or discomfort at injection site.
  • Fluid overload: excess extracellular fluid volume.

Serious or Rare Side Effects

  • Severe electrolyte imbalance: potentially life‑threatening shifts.
  • Metabolic alkalosis: excessive bicarbonate leading to high pH.
  • Anaphylactic reaction: rare hypersensitivity response.
  • Cardiac arrhythmia: abnormal heart rhythm due to electrolyte disturbances.
  • Hypotension: sudden drop in blood pressure during rapid infusion.
  • Pulmonary edema: fluid accumulation in lungs from overload.

Precautions & Warnings

When using Multibic, clinicians should observe several safety measures.

  • Monitor serum electrolytes: regularly check sodium, chloride, calcium, and magnesium levels.
  • Adjust infusion rate: tailor to the patient’s fluid status and clinical response.
  • Use with caution in heart failure: risk of fluid overload.
  • Avoid in severe hypercalcemia or hypermagnesemia: may exacerbate toxicity.
  • Contraindicated in known hypersensitivity to any component.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Multibic can interact with other medicines that affect electrolyte balance.

Major Interactions (Avoid)

  • Concurrent calcium supplements: may cause hypercalcemia.
  • Additional bicarbonate solutions: risk of metabolic alkalosis.
  • High‑dose diuretics: can intensify electrolyte shifts.
  • Sodium‑rich medications: may lead to hypernatremia.
  • Magnesium‑containing antacids: increase risk of hypermagnesemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: monitor potassium and renal function.
  • Loop diuretics: watch for calcium loss.
  • NSAIDs: may affect renal clearance of electrolytes.
  • Beta‑blockers: observe blood pressure changes.
  • Anticoagulants used in dialysis: monitor for bleeding risk.

Frequently Asked Questions

Multibic is an injectable electrolyte solution used primarily as a haemodialysis fluid and for intravenous electrolyte replacement. It supplies essential ions and a bicarbonate buffer to help maintain acid‑base balance and electrolyte homeostasis in patients undergoing renal replacement therapy or requiring IV electrolyte correction.

Sodium hydrogen carbonate provides bicarbonate ions that act as a physiological buffer, helping to correct metabolic acidosis. Together with sodium, chloride, calcium, and magnesium ions, it restores plasma electrolyte concentrations, supports osmotic balance, and facilitates normal cellular function during dialysis or intravenous therapy.

The dosage of Multibic is determined by the prescribing clinician based on the patient’s electrolyte status, fluid requirements, and the specific dialysis protocol. Healthcare professionals calculate the appropriate infusion volume and rate to achieve the desired electrolyte and acid‑base targets.

Safety data for Multibic in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Multibic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Multibic combines sodium hydrogen carbonate, magnesium chloride, sodium chloride, and calcium chloride in a single formulation, offering a comprehensive electrolyte and bicarbonate profile. Compared with solutions that contain only sodium chloride or separate bicarbonate additives, Multibic reduces the need for multiple infusions and simplifies electrolyte management during dialysis.

Multibic should be stored at ambient temperature, kept in its original packaging, and protected from direct light and moisture. Ensure the container is sealed tightly to prevent contamination, and inspect for any particulate matter before use.

Multibic is administered intravenously, either as a direct infusion during haemodialysis or as an IV electrolyte replacement. The solution is added to the dialysis circuit or infused through a controlled IV line, with the rate adjusted according to the patient’s clinical parameters.

The most serious risks include severe electrolyte imbalance, metabolic alkalosis, cardiac arrhythmias, anaphylactic reactions, and fluid overload leading to pulmonary edema. Continuous monitoring of serum electrolytes and patient vitals is essential to detect and manage these complications promptly.

Multibic should not be used in patients with known hypersensitivity to any of its components, in those with severe hypercalcemia, hypermagnesemia, or uncontrolled fluid overload. Clinicians should also exercise caution in patients with severe heart failure or uncontrolled hypertension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT