Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra)

Sodium hydrogen carbonate (bicarbonate) acts as a systemic buffer. When infused, it combines with excess hydrogen ions to form carbonic acid, which is then converted to carbon dioxide and water, raising blood pH toward normal levels. The accompanying electrolytes replace those lost during dialysis, supporting cellular and cardiac function.

The dose of Multibic is individualized. The prescribing clinician determines the volume and rate based on the patient’s laboratory values, dialysis prescription and clinical condition. No fixed regimen is provided; dosing is adjusted to achieve target electrolyte and pH goals.

Safety of Multibic in pregnancy or lactation has not been fully established. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Multibic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Multibic offers a balanced combination of bicarbonate, sodium, chloride, calcium and magnesium in a single sterile formulation, which can simplify preparation compared with mixing separate electrolyte concentrates. Its composition is designed to match typical dialysis fluid requirements, but clinicians may choose alternative solutions based on specific electrolyte targets or institutional protocols.

Multibic should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight and extreme temperature fluctuations. Do not use if the vial appears cloudy, discolored or if the seal is compromised.

Multibic is administered either as an intravenous infusion or added to the dialysis circuit according to the prescribed volume and rate. Administration should be performed by qualified healthcare personnel using aseptic technique, with continuous monitoring of vital signs and laboratory parameters.

The most serious risks include severe electrolyte disturbances such as hypercalcemia, hypermagnesemia or hypernatremia, which can lead to cardiac arrhythmias, volume overload, and in rare cases, anaphylactic reactions. Prompt monitoring and adjustment of therapy are essential to mitigate these risks.

Multibic should be avoided in patients with known hypersensitivity to any of its components, untreated severe hypercalcemia, or uncontrolled metabolic alkalosis. Caution is advised for individuals with severe heart failure, fluid overload, or those receiving concurrent high‑dose calcium or bicarbonate preparations.